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Candida albicans cells respond in two distinct ways to fluconazole exposure where cells enter the Ribo-dominant state characterized by an upregulation of ribosomal-related proteins and processes, or cells enter the Stress-dominant state characterized by the upregulation of stress responses.

Clearance of engineered Salmonella which trigger regulated cell death is dependent upon the cellular 'bucket list,' which is determined both by cell death signaling pathway and by cell type infected.

Lys417 regulates the opening and closing of SARS-CoV-2 spike protein, allowing SARS-CoV-2 to maintain a delicate balance between infectiousness and evading host immune response.

The mutational flexibility of the antimalarial target dihydroorotate dehydrogenase thwarts the use of collateral sensitivity as a strategy to suppress the evolution of resistance.

In C. elegans, neuronic TRPA-1 senses bacterial accumulation by detecting indole production to up-regulate lysozyme genes via FOXO/DAF-16 in the intestine, thereby delaying microbial dysbiosis.

Nuclear phosphoinositide signaling controls telomeric gene repression and activation essential for switching expression of surface antigen genes and thus antigenic variation.

CLEVER enables the rapid manipulation and direct rescue of plus-strand RNA viruses with the shortest hands-on time to study viral variants of concern.

Genome-intact HIV-1 proviruses were detected in autopsy samples from the brain of ART-treated persons living with HIV, indicating that the virus can persist in the central nervous system.

Knocking out the FK506-binding protein in Plasmodium falciparum (PfFKBP35) affects ribosome homeostasis and results in a delayed death-like phenotype that is independent of the mode of action of FK506.