Browse our latest Microbiology and Infectious Disease articles

Page 35 of 169
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Pathogen Evolution: Exploring accidental virulence

    Daniel FQ Smith
    Experimentally evolving yeast to adhere better to plastic led to adaptations that increased their ability to cause an infection.
    Version of Record
    Insight
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Identification of key yeast species and microbe–microbe interactions impacting larval growth of Drosophila in the wild

    Ayumi Mure, Yuki Sugiura ... Yukako Hattori
    The growth of wild Drosophila larvae on fruits is promoted by a yeast releasing essential nutrients extracellularly or by a stable association with a nutrient-providing bacterium established by microbe–microbe interactions.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Soil-borne fungi alter the apoplastic purinergic signaling in plants by deregulating the homeostasis of extracellular ATP and its metabolite adenosine

    Christopher Kesten, Valentin Leitner ... Clara Sanchez-Rodriguez
    Biochemical and in vivo physiology imaging reveal that plant pathogens actively imbalance the apoplastic eAdo/eATP levels as a virulence mechanism.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16

    Huan Wang, Syed RA Rizvi ... Shozeb Haider
    Structure and simulations reveal SARS-CoV-2 NSP10 is more resistant to genetic variations than other SARS-CoV-2 NSPs and that the presence of mutations conserves structural and dynamic changes in NSP10.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Protein Kinase A: Probing ligand selectivity in pathogens

    Bryan VanSchouwen, Giuseppe Melacini
    Why does protein kinase A respond to purine nucleosides in certain pathogens, but not to the cyclic nucleotides that activate this kinase in most other organisms?
    Version of Record
    Insight
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Estimating the contribution of subclinical tuberculosis disease to transmission: An individual patient data analysis from prevalence surveys

    Jon C Emery, Peter J Dodd ... Rein MGJ Houben
    Data analysis and mathematical modelling suggest that subclinical tuberculosis contributes substantially to transmission and needs to be diagnosed and treated for effective progress towards tuberculosis elimination.
    1. Microbiology and Infectious Disease

    Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy

    Benjamin Liffner, Ana Karla Cepeda Diaz ... Sabrina Absalon
    Ultrastructure expansion microscopy unlocks new fundamental cell biology of malaria parasites, providing new insights into processes including establishment of cell polarity, organelle biogenesis, and organelle fission.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes

    Nicole A Ellis, Kevin S Myers ... Matthias P Machner
    A randomized CRISPR-based gene silencing approach overcomes functional redundancy and discovers virulence-critical gene combinations in the pathogen Legionella pneumophila.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Cervical cancer screening improvements with self-sampling during the COVID-19 pandemic

    Miriam Elfström, Penelope Grace Gray, Joakim Dillner
    Improved cervical cancer prevention through greatly increased population coverage by use of self-sampling and HPV screening during the COVID-19 pandemic.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Enterobacterales plasmid sharing amongst human bloodstream infections, livestock, wastewater, and waterway niches in Oxfordshire, UK

    William Matlock, Samuel Lipworth ... REHAB Consortium
    A geographically and temporally restricted genomic surveillance study concludes that Enterobacterales plasmid dissemination between human and non-human niches might be occurring at greater rates than previously estimated.