Browse our latest Microbiology and Infectious Disease articles

Page 37 of 169
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma

    Alex W Chan, Malgorzata Broncel ... Sebastian Lourido
    Comprehensive characterization of kinase-dependent phosphorylation in the human pathogen Toxoplasma gondii identifies a trafficking adaptor complex required for virulence factor secretion and infection.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin–antitoxin system

    René L Bærentsen, Stine V Nielsen ... Ditlev E Brodersen
    Structural analysis of the HipBST toxin–antitoxin system from E. coli shows how a toxin kinase has been split into two proteins and encodes its own inhibitor.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    SIRT-1 is required for release of enveloped enteroviruses

    Alagie Jassey, James Logue ... William T Jackson
    Enterovirus D68, a pathogen associated with a rare child paralysis disease, depends on the cellular protein SIRT-1 for release of virus, indicating that SIRT-1 may be an important therapeutic target.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    σ28-dependent small RNA regulation of flagella biosynthesis

    Sahar Melamed, Aixia Zhang ... Gisela Storz
    σ28-Dependent sRNAs fine-tune flagella synthesis, with one sRNA connecting synthesis with metabolism and two sRNAs with opposing effects connecting synthesis with ribosomal protein production through unique binding within coding sequences.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    A modelled analysis of the impact of COVID-19-related disruptions to HPV vaccination

    Louiza S Velentzis, Megan A Smith ... Karen Canfell
    Results from this modelled analysis indicate that short-term delays in HPV vaccination of adolescents are unlikely to have substantial long-term effects on HPV-related cancers, provided catch-up of missed vaccine doses can be implemented.
    1. Microbiology and Infectious Disease

    Erythrocyte invasion-neutralising antibodies prevent Plasmodium falciparum RH5 from binding to basigin-containing membrane protein complexes

    Abhishek Jamwal, Cristina F Constantin ... Matthew K Higgins
    The most effective growth-neutralising antibodies which target the PfRH5 protein from a malaria parasite function by preventing the parasite from binding to basigin-containing membrane protein complexes on human erythrocytes.
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Development: Unlocking the microbiome

    Rosana BR Ferreira, L Caetano M Antunes
    Individual species of bacteria and yeast present in the food of wild fruit flies work together to provide the nutrients needed for larval growth.
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    Insight
    1. Cell Biology
    2. Microbiology and Infectious Disease

    PerTurboID, a targeted in situ method reveals the impact of kinase deletion on its local protein environment in the cytoadhesion complex of malaria-causing parasites

    Heledd Davies, Hugo Belda ... Moritz Treeck
    A new mass spectrometry-based method to identify and quantify changes in a subcellular local protein environment shows the impact of deletion of a kinase the human malaria parasites export into the host cell.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Dissecting the phase separation and oligomerization activities of the carboxysome positioning protein McdB

    Joseph L Basalla, Claudia A Mak ... Anthony G Vecchiarelli
    Carbon-fixing organelles, called carboxysomes, link to their spatial organization system in the bacterial cell by a hexameric protein that forms pH-dependent condensates via a nuanced multidomain mechanism.