Browse our latest Microbiology and Infectious Disease articles

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    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    A Vibrio cholerae viral satellite maximizes its spread and inhibits phage by remodeling hijacked phage coat proteins into small capsids

    Caroline M Boyd, Sundharraman Subramanian ... Kimberley D Seed
    A phage parasite encodes an external scaffolding protein to pirate and rearrange phage-encoded coat proteins to more efficiently transfer the phage parasite genome to new hosts and limit phage production.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    The infection-tolerant white-footed deermouse tempers interferon responses to endotoxin in comparison to the mouse and rat

    Ana Milovic, Jonathan V Duong, Alan G Barbour
    Comparing the white-footed deermouse with mice and rats in an inflammation model reveals a means for the observed infection tolerance in this key animal reservoir for several human diseases.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Selection on plastic adherence leads to hyper-multicellular strains and incidental virulence in the budding yeast

    Luke I Ekdahl, Juliana A Salcedo ... Helen A Murphy
    Yeast that were evolved to adhere to plastic surfaces for a few hundred generations became hyper-adherent and more virulent.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Pathogen Evolution: Exploring accidental virulence

    Daniel FQ Smith
    Experimentally evolving yeast to adhere better to plastic led to adaptations that increased their ability to cause an infection.
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    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Identification of key yeast species and microbe–microbe interactions impacting larval growth of Drosophila in the wild

    Ayumi Mure, Yuki Sugiura ... Yukako Hattori
    The growth of wild Drosophila larvae on fruits is promoted by a yeast releasing essential nutrients extracellularly or by a stable association with a nutrient-providing bacterium established by microbe–microbe interactions.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Soil-borne fungi alter the apoplastic purinergic signaling in plants by deregulating the homeostasis of extracellular ATP and its metabolite adenosine

    Christopher Kesten, Valentin Leitner ... Clara Sanchez-Rodriguez
    Biochemical and in vivo physiology imaging reveal that plant pathogens actively imbalance the apoplastic eAdo/eATP levels as a virulence mechanism.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16

    Huan Wang, Syed RA Rizvi ... Shozeb Haider
    Structure and simulations reveal SARS-CoV-2 NSP10 is more resistant to genetic variations than other SARS-CoV-2 NSPs and that the presence of mutations conserves structural and dynamic changes in NSP10.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Protein Kinase A: Probing ligand selectivity in pathogens

    Bryan VanSchouwen, Giuseppe Melacini
    Why does protein kinase A respond to purine nucleosides in certain pathogens, but not to the cyclic nucleotides that activate this kinase in most other organisms?
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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Estimating the contribution of subclinical tuberculosis disease to transmission: An individual patient data analysis from prevalence surveys

    Jon C Emery, Peter J Dodd ... Rein MGJ Houben
    Data analysis and mathematical modelling suggest that subclinical tuberculosis contributes substantially to transmission and needs to be diagnosed and treated for effective progress towards tuberculosis elimination.
    1. Microbiology and Infectious Disease

    Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy

    Benjamin Liffner, Ana Karla Cepeda Diaz ... Sabrina Absalon
    Ultrastructure expansion microscopy unlocks new fundamental cell biology of malaria parasites, providing new insights into processes including establishment of cell polarity, organelle biogenesis, and organelle fission.