Browse our latest Microbiology and Infectious Disease articles

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    1. Cell Biology
    2. Microbiology and Infectious Disease

    Creating an atlas of the bone microenvironment during oral inflammatory-related bone disease using single-cell profiling

    Yi Fan, Ping Lyu ... Chenchen Zhou
    Single-cell sequencing of the alveolar bone marrow of apical periodontitis reveals the cellular and molecular composition of the microenvironment and highlights an osteogenic potential within mesenchymal stem cells of inflammatory-related bone diseases.
    1. Microbiology and Infectious Disease
    2. Biochemistry and Chemical Biology

    Principles of RNA recruitment to viral ribonucleoprotein condensates in a segmented dsRNA virus

    Sebastian Strauss, Julia Acker ... Ralf Jungmann
    Spatial transcriptomics analysis of rotavirus replication factories reveals principles of viral transcript partitioning and RNA stoichiometry in these granules.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    The forgotten people: Hepatitis B virus (HBV) infection as a priority for the inclusion health agenda

    Emily Martyn, Sarah Eisen ... Philippa C Matthews
    Hepatitis B virus infection is a neglected challenge among communities who are under-served by conventional models of healthcare, requiring enhanced interventions to reduce inequity.
    1. Microbiology and Infectious Disease

    Initiation of HIV-1 Gag lattice assembly is required for recognition of the viral genome packaging signal

    Xiao Lei, Daniel Gonçalves-Carneiro ... Paul D Bieniasz
    Initiation of the assembly of HIV-1 particles in infected cells is required to form a subviral structure that recognizes the viral RNA genome for packaging.
    1. Microbiology and Infectious Disease
    2. Immunology and Inflammation

    IL-4 and helminth infection downregulate MINCLE-dependent macrophage response to mycobacteria and Th17 adjuvanticity

    Judith Schick, Meltem Altunay ... Roland Lang
    The expression of DECTIN-2 family C-type lectin receptors on macrophages and monocytes is inhibited by the Th2 cytokine IL-4, which suggests a mechanism for inhibition of Th17 responses to MINCLE-dependent vaccination responses by underlying helminth infection.
    1. Cancer Biology
    2. Microbiology and Infectious Disease

    Beta human papillomavirus 8E6 promotes alternative end joining

    Changkun Hu, Taylor Bugbee ... Nicholas Wallace
    Human papillomavirus type 8 E6 promotes alternative end joining by compromising non-homologous end joining and homologous recombination.
    1. Microbiology and Infectious Disease

    Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system

    Fabrice Jean-Pierre, Thomas H Hampton ... George A O'Toole
    A cystic fibrosis (CF) lung microbiome-informed in vitro polymicrobial system allows for a mechanistic understanding of community-specific tolerance of Pseudomonas aeruginosa to a front-line CF antimicrobial.
    1. Ecology
    2. Microbiology and Infectious Disease

    Host-microbiome metabolism of a plant toxin in bees

    Erick VS Motta, Alejandra Gage ... Nancy Moran
    The bee gut microbiota contributes to the metabolism of the cyanogenic glycoside amygdalin.
    1. Ecology
    2. Microbiology and Infectious Disease

    Gut Bacteria: Synergy in symbiosis

    Aileen Berasategui, Hassan Salem
    Honeybees rely on their microbial gut symbionts to overcome a potent toxin found in pollen and nectar.
    Version of Record
    Insight
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Future COVID19 surges prediction based on SARS-CoV-2 mutations surveillance

    Fares Z Najar, Evan Linde ... Pratul K Agarwal
    A real-time genomic surveillance approach based on mutation analysis of SARS-CoV-2 proteins has enabled a priori prediction of surge in number of COVID19 infection cases, including those already observed in July and September 2022.