Browse our latest Microbiology and Infectious Disease articles

The enteric bacterial microbiota stimulates a highly localized interferon-lambda signal within the intestinal epithelium that protects against murine rotavirus infection.

The Spike gene expressed by the vector-based vaccine Vaxzevria bears the risk of cryptic splicing, which in turn may lead to cellular production of soluble, instead of membrane-anchored, Spike protein variants.

A novel dual genome approach that combines genetically diverse mice and a library of bacterial mutants to define the genome-wide host pathogen interactions that drive distinct outcomes to tuberculosis.

Temperature variation caused by heatwaves and diurnal fluctuations has distinct effects on host and pathogen traits at different mean temperatures, leading to large and unexpected differences in disease burden making the impact of global warming on diseases hard to predict.

Lactic acid bacteria engage a hybrid metabolism which blends features of fermentation and respiration when they perform extracellular electron transfer.

The bacterial periplasm must adapt to factors effecting the width of the cell envelope.

High-throughput sequencing of the memory T cell receptor repertoire and machine learning can predict robust antibody and CD4 T cell response to de novo hepatitis B vaccine.

MakA, a pore-forming cytotoxin produced by Vibrio cholerae, forms oligomers and remodels membranes into high-curvature tubes, resulting in membrane integrity loss inside acidified organelle lumens or when cultured with cells in an acidic medium.

A critical role for bacterial lytic transglycosylases in the clearance of novel, toxic cell wall turnover products that accumulate during vegetative growth is identified through genetic approaches and compositional analysis of solubilized peptidoglycan released from the bacterial cell wall.

Under starvation conditions, anti-carD antisense RNA and Clp protease work together to decrease the CarD level to mediate the adaptation and survival of mycobacterial cells.