Browse our latest Microbiology and Infectious Disease articles

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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Human genetic ancestry, Mycobacterium tuberculosis diversity, and tuberculosis disease severity in Dar es Salaam, Tanzania

    Michaela Zwyer, Zhi Ming Xu ... Daniela Brites
    The severity of active tuberculosis in a high-burden population is not explained by host or pathogen genetic variation, suggesting a dominant role for social and environmental factors.
    1. Microbiology and Infectious Disease

    4-Aminoquinolines block heme iron reactivity and interfere with artemisinin action

    Melissa Rosenthal, Daniel E Goldberg
    Chloroquine interferes with artemisinin activation, and such interactions should be considered when formulating antimalarial drug combinations.
    1. Microbiology and Infectious Disease

    Gut Microbiome: Bacteria weigh up costs and benefits of mobile weapons

    Zhao Wang, Yang Fu
    Gaining the ability to kill rival microbes is not always an advantage for bacteria in complex gut microbiomes.
    Version of Record
    Insight
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Expression of specific var gene subtypes is differentially associated with severe malaria syndromes

    Henry Ndugwa, Michelle Muthui ... Abdirahman I Abdi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease

    Mycobacterial metallophosphatase MmpE acts as a nucleomodulin to regulate host gene expression and promote intracellular survival

    Liu Chen, Baojie Duan ... Aizhen Guo
    Mycobacterium tuberculosis utilizes nucleomodulins to disrupt host inflammatory responses and lysosomal maturation, uncovering a novel strategy for immune evasion and intracellular survival.
    1. Microbiology and Infectious Disease

    Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival

    Nicholas A Bates, Ronald Rodriguez ... Bennett H Penn
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    Mycobacterium tuberculosis suppresses protective Th17 responses during infection

    Alex Zilinskas, Amir Balakhmet ... Sarah A Stanley
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Automated genome mining predicts structural diversity and taxonomic distribution of peptide metallophores across bacteria

    Zachary L Reitz, Bita Pourmohsenin ... Marnix H Medema
    Automated detection of metallophore biosynthesis reveals that metal-chelating non-ribosomal peptides are widespread, chemically diverse, and deeply rooted in bacterial evolution.
    1. Microbiology and Infectious Disease

    Evaluation of antibiotic and peptide vaccine strategies for mirror bacterial infections

    Alexander Kleinman, Joe Torres, Brian Wang
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Microbiology and Infectious Disease

    Chemostat culturing reduces fecal eukaryotic virus load and delays diarrhea after virome transplantation

    Simone Margaard Offersen, Signe Adamberg ... Anders Brunse
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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