Browse our latest Microbiology and Infectious Disease articles

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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Redirection of SARS-CoV-2 to phagocytes by intranasal sACE2-Fc as a universal decoy confers complete prophylactic protection

    Jingyi Wang, Jiangchuan Li ... Bo Feng
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease

    The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2

    Rahul K Suryawanshi, Priyadarshini Jaishankar ... James S Fraser
    The development of new small molecules demonstrates how pharmacologic inhibition of the coronavirus macrodomain restores innate immunity, leading to reduced viral replication and improved outcomes in severe infection.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective

    Timothy J Henrich, Christopher P Montgomery ... Maria Laura Gennaro
    Unraveling mechanisms underlying post-acute SARS-CoV-2 sequelae (long COVID) and finding therapeutic solutions require a full understanding of the causative role of SARS-CoV-2 persistence and/or infection with other microorganisms, which may be pre-existing, concurrent, or subsequent to acute COVID-19.
    1. Microbiology and Infectious Disease

    Nanoscopy Reveals Heparan Sulfate Clusters as Docking Sites for SARS-CoV-2 Attachment and Entry

    Sue Han, Xin Wang ... Ling-Gang Wu
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Microbiology and Infectious Disease

    Apparent cooperativity between human CMV virions introduces errors in conventional methods of calculating multiplicity of infection

    Christopher Peterson, Joshua Miller ... Vitaly V Ganusov
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Innate immune memory: The evolving role of macrophages in therapy

    Payal Damani-Yokota, Kamal Mohan Khanna
    Epigenetic and metabolic programming of innate immune cells shapes host defense and disease susceptibility.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Repeated vaccination with homologous influenza hemagglutinin broadens human antibody responses to unmatched flu viruses

    Yixiang Deng, Melbourne Tang ... Daniel Lingwood
    Classical antibody boosting effects during vaccination are accompanied by natural broadening mechanisms that help enable human antibodies to engage conserved sites of vulnerability on influenza virus.
    1. Microbiology and Infectious Disease

    Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival

    Nicholas A Bates, Ronald Rodriguez ... Bennett H Penn
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease
    3. Medicine

    Focus Issue: Trained Immunity

    Edited by Satyajit Rath et al.
    Our latest Focus Issue looks at what we’ve learnt over the past decade and what’s next for the field of trained immunity.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Focus Issue: Evolving our understanding of trained immunity

    Eva Kaufmann, Yahya Sohrabi ... Jos WM van der Meer
    The articles in this focus issue discuss progress towards a more complete understanding of memory in the innate immune system, and efforts to exploit "trained immunity" for the development of new vaccines and therapeutics.
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