Browse our latest Microbiology and Infectious Disease articles

Intermolecular steric repulsion generated by glycans on the cell membrane inhibits viral infection by preventing the formation of a virus-cell interface, regardless of the identity of molecules for glycan modification.

Evolutionary changes in RNA binding and antiviral activity result in diverse IFIT1 functions across mammals, even among closely related species.

The pneumococcal capsular serotype and genetic background, as well as a combination of genomic loci, influence intrinsic pneumococcal growth kinetics, which may have implications for pneumococcal disease pathogenesis.

High-content high-resolution microscopy coupled with deep learning-based analysis reveals novel phenotypes at the single-cell level during Shigella infection.

Myc dysregulation in activated macrophages impairs antioxidant defenses, locking them in a vicious cycle that amplifies type I interferon signaling, driving hyperinflammation and immunosuppression.

A biochemical and bioinformatics approach shows how T6SS immunity proteins bind to and neutralize a range of non-cognate effectors, which is critical for promoting bacterial fitness in mixed-strain environments.

Drug repurposing screens reveal several epigenetic inhibitors as active against P. vivax hypnozoites demonstrating that epigenetic pathways play a central role in hypnozoite quiescence.