Browse our latest Microbiology and Infectious Disease articles

Page 7 of 170
    1. Microbiology and Infectious Disease

    Unraveling CRP/cAMP-mediated metabolic regulation in Escherichia coli persister cells

    Han G Ngo, Sayed Golam Mohiuddin ... Mehmet Orman
    CRP/cAMP plays a crucial role in the metabolic shift of Escherichia coli persisters from an anabolic state to oxidative phosphorylation, which is essential for their survival during antibiotic treatment.
    1. Microbiology and Infectious Disease

    Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA

    Bastien Casu, Joseph W Sallmen ... Susan Schlimpert
    CryoEM, genetic, and cell biological analyses reveal that the conserved membrane protein CisA mediates membrane recruitment of contractile injection systems Streptomyces coelicolor, enabling their activation under stress.
    1. Microbiology and Infectious Disease

    Heat stress induces phage tolerance in Enterobacteriaceae

    Fan Zhang, Hao-Ze Chen ... Jia-Feng Liu
    Bacterial persistence against phages enables survival under infection, and heat treatment enhances this tolerance, facilitating resistance evolution and influencing the effectiveness of phage therapy.
    1. Microbiology and Infectious Disease

    The impact of different antimicrobial exposures on the gut microbiome in the ARMORD observational study

    Leon Peto, Nicola Fawcett ... A Sarah Walker
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease

    The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T cell recognition by targeting CIITA

    Fabienne Maassen, Vu Thuy Khanh Le-Trilling ... Mirko Trilling
    Through the destabilization of CIITA, the human cytomegalovirus-encoded protein pUS28 antagonizes the expression of the HLA-II molecules CD74/Ii, HLA-DR, HLA-DQ, HLA-DM, and HLA-DP, diminishing the activation of HCMV-specific CD4+ T cells and reducing their secretion of antiviral cytokines.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Heterogeneous efflux pump expression underpins phenotypic resistance to antimicrobial peptides

    Ka Kiu Lee, Urszula Łapińska ... Stefano Pagliara
    Sub-populations of non growing bacteria survive treatment with antimicrobial peptides by mounting an efflux response.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Doubling dolutegravir dosage reduces the viral reservoir in ART-treated people with HIV

    Céline Fombellida-Lopez, Aurelija Valaitienė ... Gilles Darcis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease

    SIRT2 protects against Japanese encephalitis virus infection in mice

    Perumal Arumugam Desingu, Lavanya Dindi ... Nagalingam R Sundaresan
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Distinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin

    Cheryll M Sia, Rebecca L Ambrose ... Danielle J Ingle
    The most comprehensive analysis of Salmonella Dublin to date uncovers distinct genotypic adaptations, antimicrobial resistance patterns, and virulence strategies that influence epidemiological success.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Myosin light chain 3 serves as a receptor for nervous necrosis virus entry into host cells via the macropinocytosis pathway

    Lan Yao, Wanwan Zhang ... Kuntong Jia
    MYL3 is identified as a novel receptor enabling nervous necrosis virus (NNV) entry via macropinocytosis, revealing a therapeutic target for combating NNV outbreaks in aquaculture.