Katrina M Zinn, Mathew W McLaren ... Matthew J Elrick
Enterovirus D68, a cause of acute flaccid myelitis, disrupts the composition and function of the nuclear pore complex primarily through its 2A protease, which is also toxic to motor neurons.
In an assay focusing on active virus recruitment rather than passive binding, STED microscopy reveals early association of virions to CD151, indicating its early involvement in viral entry platforms formation.
Fernanda T Subtil, Teresa FG Machado ... Luiz Pedro S de Carvalho
Using macroevolution, species not strains, uncovered important diversity in how mycobacteria respond to and resist antibiotics, revealing novel resistance determinants.
Helge Feddersen, Charlotte Dyckmans, Marc Bramkamp
Dynamic relocalization of MinD in Bacillus subtilis arises from membrane binding of monomers and dimers with membrane-triggered ATP hydrolysis, suggesting MinE-like activators are unnecessary for Min system dynamics.
Transcriptome-wide profiling of bacterial RNA pseudouridylation maps modification landscapes and nominates candidate regulatory sites, offering a resource and foundation for future mechanistic studies of Ψ function in bacteria.
Interaction between LFA-1 on natural killer cells and GBP-130 on infected erythrocytes enables immune recognition and killing of Plasmodium falciparum-infected red blood cells.
