Amanda Mixon Blackwell, Yasaman Jami-Alahmadi ... Paul A Sigala
Plasmodium parasites have repurposed the heme oxygenase scaffold from its canonical heme-degrading function to fulfill an essential and adaptive role in gene expression within the apicoplast organelle.
Benedikt M Mortzfeld, Shakti K Bhattarai, Vanni Bucci
12 new class IIb microcins have been structurally identified, phylogenetically assessed, and functionally tested for their antimicrobial activity, increasing the total number of these bacteriocins to 17.
Priya M Christensen, Jonathan Martin ... Kelli L Palmer
A previously unknown lipid modification by a bacterial antibiotic resistance enzyme was identified through the analysis of a family of antibiotic resistance enzyme sequences with a machine learning approach.
Francesca Torelli, Diogo M da Fonseca ... Moritz Treeck
Secreted effector proteins of Toxoplasma gondii parasites create a supportive immune environment in mice, allowing individually less fit mutants to thrive and evade detection by in vivo CRISPR screens.
Zeinab M Chahine, Mohit Gupta ... Karine G Le Roch
The PfMORC protein is proven to play a crucial role in chromatin structure, gene regulation and heterochromatin stability, categorizing PfMORC as a strong potential candidate for novel therapeutic interventions.
Clara Bekirian, Isabel Valsecchi ... Thierry Fontaine
β-1,6-Glucan is crucial for Candida albicans cell wall structure and integrity, adapting dynamically to environmental stresses and compensating for mannan deficiencies in cell wall organization.