Microbiology and Infectious Disease

Latest articles

1. 1. Microbiology and Infectious Disease

   Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir

   Jason Neidleman et al.

   An in-depth view of the in vivo blood and tissue HIV reservoir is presented highlighting shared phenotypic features between individuals, thus enabling marked ex vivo enrichment of replication-competent latent cells.
2. 1. Microbiology and Infectious Disease

   Defining the function of OmpA in the Rcs stress response

   Kilian Dekoninck et al.
3. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death

   Kuan-Yi Lu et al.

   Phosphatidylinositol 3-phosphate interacts with PfHsp70-1 and stabilizes the Plasmodium digestive vacuole under febrile temperatures.
4. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels

   Elisa Gómez-Gil et al.

   Microscopic and biochemical analysis show that the stress-activated MAP kinase pathway targets the formin For3 to modulate actomyosin ring integrity in response to environmental cues.
5. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement

   Jie Zhang et al.

   A systematic set of experiments reveals how properdin specifically directs AP activation independently of primary C3 deposition additionally as an alternative convertase stabilizer, thus revising immune machinery of complement activation.
6. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Genome duplication in Leishmania major relies on persistent subtelomeric DNA replication

   Jeziel Dener Damasceno et al.

   Duplication of Leishmania chromosomes combines S-phase DNA replication initiated at a single internal region with subtelomeric DNA replication detectable outside S-phase, potentially explaining genome plasticity in this important parasite.
7. 1. Microbiology and Infectious Disease
   2. Structural Biology and Molecular Biophysics

   Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex

   Clarissa L Durie et al.

   The structure of the Legionella pneumophilaType IV secretion system provides the detailed molecular model of this complex molecular machine required for pathogenesis.
8. 1. Microbiology and Infectious Disease

   Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex

   Michael J Sheedlo et al.

   The structure of a Type IV secretion system provides a framework for understanding assembly of a protein-injection machine.
9. 1. Microbiology and Infectious Disease

   Unbiased homeologous recombination during pneumococcal transformation allows for multiple chromosomal integration events

   Jun Kurushima et al.
10. 1. Microbiology and Infectious Disease

    Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis

    Jennifer L Elliott et al.