Purkinje cell collaterals regulate processing in the input layer of the cerebellum by providing fast stochastic GABAA-mediated and slow GABAB-mediated inhibition to a specialized subset of unipolar brush cells.
The statistics of binocular rivalry at different combinations of image contrast is reproduced quantitatively by competing out-of-equilibrium populations of independent neural assemblies with idealized attractor dynamics.
Although flies cannot discriminate shock-paired and -unpaired odor 24 hr after single-trial aversive conditioning, they choose to avoid both of them, which is derived from a merged long-term memory.
Adult microglia are born by the division of single surviving microglia that rapidly acquire mature morphologies and functions in order to perform their physiological roles in the brain.
Single-cell RNA-sequencing and neural circuitry analyses reveal that sensorimotor transformation of different behaviors which are performed by separate circuit modules in the superior colliculus are molecularly defined by distinct transcriptomic codes of specific neuron subtypes.
Amicia D Elliott, Adama Berndt ... Benjamin H White
The elementary units of a fruit fly behavioral sequence are described at single-muscle resolution and shown to exhibit variability that is subject to neuromodulatory regulation.
Stephen Johnston, Sarah L Parylak ... Matthew Shtrahman
Future work using recombinant AAV as an experimental tool in the dentate gyrus or as a gene therapy for diseases of the central nervous system should be carefully evaluated.
Steven R Sando, Nikhil Bhatla ... H Robert Horvitz
By driving the localized contraction of subcellular muscle regions, a single motor neuron reverses the flow of material in the Caenorhabditis elegans pharynx, a neuromuscular pump, converting feeding into spitting.