Friederike E Kohrs, Ilsa-Maria Daumann ... P Robin Hiesinger
The first complete null mutant collection of all rab GTPase genes in a multicellular organism uncovers neuronal development and function sensitive to environmental challenges in Drosophila.
Rafael Renteria, Christian Cazares ... Christina M Gremel
Chronic alcohol exposure results in a long-lasting, enhanced endocannabinoid signalling at orbitostriatal synapses that is expressed in a projection-, synapse-, and behaviorally computation-specific manner.
All-trans retinoic acid induces functional and structural plasticity of synapses in human cortical circuits through the engagement of the spine apparatus.
Neuropeptide tachykinin signaling acts as master regulator of behavioral specialization in honeybees by differentially modulating worker responsiveness to task-specific stimuli.
FlyBrainLab is an open-source computing platform that integrates 3D exploration and visualization of diverse Drosophila connectomic/synaptomic datasets with interactive exploration of the functional logic of modeled executable brain circuits.
The human brain maintains a representation of latent task states within frontoparietal networks during the generalization of behaviors to novel settings.
Bassam Tawfik, Joana S Martins ... Jakob Balslev Sørensen
Synaptotagmin-7 acts synergistically with synaptotagmin-1 by placing vesicles close to the plasma membrane within reach of the SNARE/Munc13-complex, supporting their priming and setting the stage for fast and slow fusion.
Roberto de Filippo, Benjamin R Rost ... Dietmar Schmitz
Somatostatin interneurons are novel mediators of serotonergic modulation in entorhinal cortex via activation of 5-HT2A receptors, a receptor involved in the etiology of different psychiatric disorders.
A deep learning-based pipeline was developed for extracting cellular signals flexibly from moving cells in 3D time lapse images, and it outperformed previous methods under different imaging conditions.
