Browse our latest Neuroscience articles

Page 455 of 646
    1. Neuroscience

    Valence-encoding in the lateral habenula arises from the entopeduncular region

    Hao Li, Dominika Pullmann, Thomas C Jhou
    Lateral habenula neurons participate in motivated behavior via their activation by negative affective stimuli, a major source of which arises from the rostral entopeduncular nucleus.
    1. Neuroscience

    Extrinsic and intrinsic dynamics in movement intermittency

    Damar Susilaradeya, Wei Xu ... Andrew Jackson
    The rhythmicity in upper-limb tracking movements and associated population dynamics in primary motor cortex is explained by a feedback controller incorporating optimal state estimation.
    1. Neuroscience

    A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites

    Nan Jiang, Jeffrey P Rasmussen ... Jay Z Parrish
    Epidermal cells in vertebrates and invertebrates ensheath portions of somatosensory neurons via a conserved morphogenetic mechanism, and this ensheathment regulates morphogenesis and function of Drosophila nociceptive neurons.
    1. Neuroscience

    Cortico-hippocampal network connections support the multidimensional quality of episodic memory

    Rose A Cooper, Maureen Ritchey
    Enhanced hippocampal-cortical network communication during memory retrieval flexibly tracks the quality and content of memories for complex past events.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

    M Catarina Silva, Fleur M Ferguson ... Stephen J Haggarty
    A new Cereblon-recruiting bifunctional tau ligand, QC-01-175, promotes aberrant tau degradation and rescue of stress vulnerability in human neuronal cell models of tauopathy.
    1. Neuroscience

    Behavioural and neural signatures of perceptual decision-making are modulated by pupil-linked arousal

    Jochem van Kempen, Gerard M Loughnane ... Mark A Bellgrove
    A direct relationship between pupil diameter and electrophysiological correlates of attention, sensory stimulus processing and target detection was observed demonstrating that arousal has a substantial influence on perceptual decision-making.
    1. Neuroscience

    Sensory prediction errors in the human midbrain signal identity violations independent of perceptual distance

    Javier A Suarez, James D Howard ... Thorsten Kahnt
    Activity in the midbrain responds to unexpected changes in outcome identity (i.e. sensory prediction error) but does not scale with perceptual distance between expected and receipt reward.
    1. Computational and Systems Biology
    2. Neuroscience

    Narrow equilibrium window for complex coacervation of tau and RNA under cellular conditions

    Yanxian Lin, James McCarty ... Songi Han
    Liquid-liquid phase separation of tau is demonstrated to be an equilibrium state, stable only within a narrow range near physiological conditions, and thus has the capacity to regulate biological processes.
    1. Developmental Biology
    2. Neuroscience

    Chronology-based architecture of descending circuits that underlie the development of locomotor repertoire after birth

    Avinash Pujala, Minoru Koyama
    Newly forming descending pathways are arranged to function in parallel to existing ones and contribute to increasingly sophisticated locomotor behaviors that emerge postnatally with suitable connectivity patterns and biophysical properties.
    1. Neuroscience

    Locomotion: Building behaviors, one layer at a time

    Claire Wyart, Vatsala Thirumalai
    New interneurons are added in the hindbrain to support more complex movements as young zebrafish get older.
    Version of Record
    Insight