Browse our latest Neuroscience articles

Page 469 of 599
    1. Neuroscience

    Subcellular analysis of pigeon hair cells implicates vesicular trafficking in cuticulosome formation and maintenance

    Simon Nimpf, Erich Pascal Malkemper ... David A Keays
    Cuticulosomes are organelles found in the hair cells of birds that are composed of ferritin nanoparticles, form rapidly after hatching by the fusion of vesicular structures, and may play an indirect role in magnetic sensation.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Fundamental constraints in synchronous muscle limit superfast motor control in vertebrates

    Andrew F Mead, Nerea Osinalde ... Coen PH Elemans
    Vertebrate superfast muscles employ similar excitation–contraction strategies but distinct myosin heavy chain genes to allow superfast performance, revealing a maximum speed that cannot be overcome without sacrificing neural control.
    1. Neuroscience

    Defective synaptic transmission causes disease signs in a mouse model of juvenile neuronal ceroid lipofuscinosis

    Benedikt Grünewald, Maren D Lange ... Christian Geis
    Impaired GABAergic and glutamatergic synaptic function and loss of interneurons in the amygdala, hippocampus, and cerebellum cause characteristic disease symptoms in a mouse model juvenile neuronal ceroid lipofuscinosis.
    1. Neuroscience

    Risk of punishment influences discrete and coordinated encoding of reward-guided actions by prefrontal cortex and VTA neurons

    Junchol Park, Bita Moghaddam
    Risk of punishment during reward seeking behavior is associated with a functional "disconnection" of the PFC-VTA circuit due to a transient loss of VTA-driven theta oscillation.
    1. Cell Biology
    2. Neuroscience

    RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation

    Kei Nakayama, Rie Ohashi ... Nobuyuki Shiina
    The formation of long-term memory in mice requires an element of RNA granules that localizes messenger RNAs to dendrites.
    1. Neuroscience

    Cocaine-induced adaptation of dopamine D2S, but not D2L autoreceptors

    Brooks G Robinson, Alec F Condon ... Kim A Neve
    Desensitization of the D2 autoreceptor is reduced following in vivo cocaine exposure due to plasticity in the D2S and not the D2L splice variant.
    1. Neuroscience

    Small molecule Photoregulin3 prevents retinal degeneration in the RhoP23H mouse model of retinitis pigmentosa

    Paul A Nakamura, Andy A Shimchuk ... Thomas A Reh
    Regulating rod gene expression with a small molecule ligand for the orphan nuclear receptor Nr2e3 rescues photoreceptors from degeneration in a mouse model of retinitis pigmentosa.
    1. Neuroscience

    CD40 is a major regulator of dendrite growth from developing excitatory and inhibitory neurons

    Paulina Carriba, Alun M Davies
    CD40-activated CD40L-mediated reverse signalling has strikingly opposite effects on the growth of excitatory and inhibitory neuron dendrites in the developing brain of mice.
    1. Computational and Systems Biology
    2. Neuroscience

    The formation of the light-sensing compartment of cone photoreceptors coincides with a transcriptional switch

    Janine M Daum, Özkan Keles ... Botond Roska
    Correlating changes in structure and gene expression in cone photoreceptors of mice daily, between birth and eye opening, created a resource that supports research in photoreceptor function, development, transplantation and repair.
    1. Neuroscience

    A unified internal model theory to resolve the paradox of active versus passive self-motion sensation

    Jean Laurens, Dora E Angelaki
    Central vestibular regions in the brainstem and cerebellum perform dynamic Bayesian inference to combine motor commands and sensory signals into an optimal estimate of self-motion.