Browse our latest Neuroscience articles

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    1. Neuroscience

    Pain-Related Memory Impairment: How does chronic pain lead to memory loss?

    Suelen Pereira, Ivan Tomsic ... Mychael V Lourenco
    A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.
    Version of Record
    Insight
    1. Neuroscience

    Opioids: Finding new ways to treat overdoses

    Jill R Turner, Jocelyn Martin
    Reversing opioid overdoses in rats using a drug that does not enter the brain prevents the sudden and severe withdrawal symptoms associated with therapeutics that target the central nervous system.
    Version of Record
    Insight
    1. Neuroscience

    Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection

    Ilya A Rybak, Natalia A Shevtsova ... Alain Frigon
    Computational modeling based on experimental data reveals how spinal sensorimotor circuits control cycle and phase durations during treadmill locomotion after an incomplete spinal cord injury.
    1. Neuroscience

    Discriminating neural ensemble patterns through dendritic computations in randomly connected feedforward networks

    Bhanu Priya Somashekar, Upinder Singh Bhalla
    In feedforward networks with random connectivity, connection motifs underlying the detection of short clusters and activity sequences are likely to converge on a subset of postsynaptic neurons purely by chance.
    1. Neuroscience

    Automated cell annotation in multi-cell images using an improved CRF_ID algorithm

    Hyun Jee Lee, Jingting Liang ... Hang Lu
    Highly accurate automated cell annotation in multi-cell imaging enables cell identification and reduces subjectivity in Caenorhabditis elegans neural image processing.
    1. Neuroscience

    A split-GAL4 driver line resource for Drosophila neuron types

    Geoffrey W Meissner, Allison Vannan ... FlyLight Project Team
    Thousands of cell-type-specific split-GAL4 driver lines and a massive, searchable image collection enable Drosophila neuroscientists to target neurons of interest with increased precision.
    1. Cell Biology
    2. Neuroscience

    DIO-SPOTlight Transgenic Mouse to Functionally Monitor Protein Synthesis Regulated by the Integrated Stress Response

    Matthew L Oliver, Zachary F Caffall ... Nicole Calakos
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Sensory experience controls dendritic structure and behavior by distinct pathways involving degenerins

    Sharon Inberg, Yael Iosilevskii ... Benjamin Podbilewicz
    Mechanosensory isolation of C. elegans nematodes independently induces homeostatic structural changes in the dendritic tree and differential response to mechanical stimulation, both these structural and behavioral outcomes are mediated by degenerins and do not affect presynaptic calcium dynamics.
    1. Neuroscience

    Projections from thalamic nucleus reuniens to hippocampal CA1 area participate in context fear extinction by affecting extinction-induced molecular remodeling of excitatory synapses

    Magdalena Ziółkowska, Narges Sotoudeh ... Kasia Radwanska
    Confocal and electron microscopy analyses reveal that contextual fear extinction induces structural remodeling of thalamic projections to the CA1 area of the hippocampus.
    1. Neuroscience

    Deficiency of orexin receptor type 1 in dopaminergic neurons increases novelty-induced locomotion and exploration

    Xing Xiao, Gagik Yeghiazaryan ... Anne Christine Hausen
    Ox1R signaling in dopaminergic neurons regulates context-induced locomotor activity and exploration in mice.
    Version of Record
    Short Report
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    • Solid