Neuroscience

Neuroscience

eLife publishes research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Neuroscience

    Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

    Max Koppers et al.
    Multiple axonal guidance receptors control the local and selective translation of mRNAs by binding to ribosomes, specific mRNAs and RNA-binding proteins.
    1. Neuroscience

    Reliability of an interneuron response depends on an integrated sensory state

    May Dobosiewicz et al.
    A pair of interneurons in C. elegans condenses information from multiple sensory neurons into a uniform response, using an AND-gate logic to represent a stimulus with positive valence.
    1. Neuroscience

    Single cell transcriptome atlas of the Drosophila larval brain

    Clarisse Brunet Avalos et al.
    Single-cell transcriptomics identifies cellular composition of the first instar Drosophila brain and the response to starvation.
    1. Neuroscience

    High-throughput microcircuit analysis of individual human brains through next-generation multineuron patch-clamp

    Yangfan Peng et al.
    Combining a multineuron patch-clamp system with an automated pipette pressure and cleaning device enables efficient screening of synaptic connectivity in human brain slices and allows inter-individual comparison.
    1. Developmental Biology
    2. Neuroscience

    Gradient-independent Wnt signaling instructs asymmetric neurite pruning in C. elegans

    Menghao Lu, Kota Mizumoto
    Genetic analyses revealed the critical role of local Wnt in neuronal patterning by instructing neurite pruning.
    1. Neuroscience

    The representational space of observed actions

    Raffaele Tucciarelli et al.
    Representational similarity analysis of human functional magnetic resonance imaging data demonstrates that the lateral occipitotemporal cortex represents action knowledge along dimensions that are in accordance with behavioural judgements.
    1. Neuroscience

    Spatiotemporal constraints on optogenetic inactivation in cortical circuits

    Nuo Li et al.
    Electrophysiology measurements characterized eight optogenetic methods, including a new reporter mouse expressing soma-localized light-activated chloride channels, for inactivating small regions of mouse neocortex.
    1. Neuroscience

    Interhemispherically dynamic representation of an eye movement-related activity in mouse frontal cortex

    Takashi R Sato et al.
    Optogenetically induced motor disruption can evoke plasticity in the mouse frontal cortex that compensates for the motor deficits, accompanying changes in inter-hemispheric motor representation.
    1. Developmental Biology
    2. Neuroscience

    Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth

    Ryan T Willett et al.
    The first born excitatory cerebellar nuclei neurons influence the survival of their Purkinje cell partners which stimulate the expansion of granule cells and interneurons to produce functional local circuits.

Highlights

    1. Neuroscience

    The cerebellum shows its stripes

    Ashley L Holloway, Talia N Lerner
    1. Neuroscience

    The impact of light at night

    Sophia TC Leung et al.

Senior editors

  1. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  2. Joshua I Gold
    University of Pennsylvania, United States
  3. K VijayRaghavan
    K VijayRaghavan
    National Centre for Biological Sciences, Tata Institute of Fundamental Research, India
  4. See more editors