eLife publishes research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    A partially nested cortical hierarchy of neural states underlies event segmentation in the human brain

    Linda Geerligs, Dora Gözükara ... Umut Güçlü
    The ongoing stream of information that comes in through our senses is segmented into distinct neural states at each level of the cortical hierarchy, which underpins our experience of distinct events.
    1. Neuroscience

    The Neurodata Without Borders ecosystem for neurophysiological data science

    Oliver Rübel, Andrew Tritt ... Kristofer E Bouchard
    The NWB data language enables reproduction, interchange, and reuse of diverse neurophysiology data, and the design principles of NWB are generally applicable to enhance discovery across biology through data FAIRness.
    1. Developmental Biology
    2. Neuroscience

    Sociosexual behavior requires both activating and repressive roles of Tfap2e/AP-2ε in vomeronasal sensory neurons

    Jennifer M Lin, Tyler A Mitchell ... Paolo Emanuele Forni
    In vivo genetic experiments show that aberrant expression of a transcription factor can compromise the functionality of neurons which is important to better understand the potential mechanisms underlying neuropathologies.
    1. Neuroscience

    Learning of probabilistic punishment as a model of anxiety produces changes in action but not punisher encoding in the dmPFC and VTA

    David S Jacobs, Madeleine C Allen ... Bita Moghaddam
    A novel approach to studying anxiety reveals that learned anxiety and diazepam treatment have unique roles on prefrontal cortex and ventral tegmental area activity.
    1. Neuroscience

    Repressor element 1-silencing transcription factor deficiency yields profound hearing loss through Kv7.4 channel upsurge in auditory neurons and hair cells

    Haiwei Zhang, Hongchen Li ... Ping Lv
    In the cochlea, repressor element 1-silencing transcription factor (REST) regulates the expression levels of Kv7.4 and alterations of REST functions result in progressive hearing loss.
    1. Neuroscience

    Shared mechanisms of auditory and non-auditory vocal learning in the songbird brain

    James N McGregor, Abigail L Grassler ... Samuel J Sober
    A novel, non-auditory learning paradigm reveals that songbirds can modify their vocal output based on somatosensory signals and that a common set of brain pathways underlies both this form of vocal learning and auditory-guided vocal learning.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Rabphilin 3A binds the N-peptide of SNAP-25 to promote SNARE complex assembly in exocytosis

    Tianzhi Li, Qiqi Cheng ... Cong Ma
    A new binding mode between Rabphilin 3A and SNAP-25 enables efficient SNARE complex assembly via inducing a conformation change in SNAP-25 SNARE motif.
    1. Neuroscience

    Functional brain reconfiguration during sustained pain

    Jae-Joong Lee, Sungwoo Lee ... Choong-Wan Woo
    Human neuroimaging with time-evolving network analysis reveals dynamic interactions among multiple functional brain networks in response to sustained pain.

Senior editors

  1. Richard Aldrich
    Richard Aldrich
    The University of Texas at Austin, United States
  2. Michael J Frank
    Brown University, United States
  3. Barbara G Shinn-Cunningham
    Carnegie Mellon University, United States
  4. See more editors