Browse our latest Stem Cells and Regenerative Medicine articles

Stochastic cell migration modulates exposure to signals that regulate commitment in the nephron progenitor niche.

Several support cell populations balance progenitor maintenance with differentiation in zebrafish lateral line sensory organs.

We are writing to communicate our concerns regarding the recently published study by Lees-Shepard et al. (2018).

We respond to concerns expressed by Pacifici and Shore (2019) about our recent paper (Lees-Shepard et al., 2018a).

Integrin a11 is identified as an Osteolectin receptor, revealing a new mechanism for adult skeletal bone maintenance in which Osteolectin/a11b1 signaling promotes bone formation by activating the Wnt pathway.

A Drosophila fertility gene is identified that acts as a linker between HP1a and local H3K4 demethylation during HP1a-mediated gene silencing that is required for ovary development and transposon silencing..

Induced neuronal cells acquire epigenomic signatures specific to matured neurons.

Adult stem cells sense nearby tissue damage and recruit immune cells to help them direct efforts towards containing a breach in the epithelial barrier.

During ES cell differentiation, Yap1 directly regulates apoptosis-related genes like Bcl-2 and Mcl-1 to attenuate apoptosis and promote cell survival to allow for successful cell fate changes.

Using a lineage tracing model, it is demonstrated that adult murine hematopoiesis is contingent on the continuous output from HSCs, with quantitative contributions that are dependent on lineage-type and age.