Browse our latest Stem Cells and Regenerative Medicine articles

A subpopulation of multi-secretory hypothalamic stem cells was developed to form 3D spheres for peripheral application against mortality and symptom of a severe diabetes model.

Naive hPSCs can readily give rise to human trophoblast stem cells, thus demonstrating their extraembryonic lineage potential and providing a new model system to study human trophectoderm specification.

Increased expression of Drosophila Tailless (TLX homologue) reverts intermediate progenitors to neural stem cells, inducing tumourigenesis via Asense repression and reflecting mutually exclusive TLX and ASCL1 expression in human glioblastoma.

Infrared laser-mediated gene induction microscopy enables precise single-cell labeling in various tissues of zebrafish, and in vivo visualized single-cell lineage tracing reveals the lineage heterogeneity in hematopoietic endothelial cells.

Cohesin-regulated 3D genome conformation controls activity of transcription factor Escargot in intestinal stem cells, prevents premature differentiation into enterocytes and maintains intestinal homeostasis.

Single-cell RNA sequencing reveals Nrg1/ErbB2-induced metabolic reprogramming as a pivotal event for cardiomyocyte proliferation during heart regeneration.

Using multiple genetic reporter system in human pluripotent stem cells, a transcriptional database for human early myogenesis has been established.

A novel CRISPR-based genetic screen of candidate regeneration genes in haploid axolotl limbs reveals two genes required for proper regeneration.

The Timothy syndrome mutation in Ca_v1.2 gives rise to defects in neuronal differentiation by preventing a developmental switch in channel splicing and elevating calcium signaling in differentiating cells.

Elucidation of the molecular basis of early wound epidermis dependence during salamander limb regeneration reveals midkine as a key modulator of wound epidermis development and wound-healing resolution.