Browse our latest Structural Biology and Molecular Biophysics articles

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    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    RNA Selectively Modulates Activity of Virulent Amyloid PSMα3 and Host Defense LL-37 via Phase Separation and Aggregation Dynamics

    Bader Rayan, Eilon Barnea ... Meytal Landau
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Protein-induced membrane strain drives supercomplex formation

    Maximilian C Pöverlein, Alexander Jussupow ... Ville RI Kaila
    Respiratory supercomplex formation relieves molecular strain of mitochondrial membranes and reshapes global protein motions, linking membrane reorganization to respiratory function.
    1. Structural Biology and Molecular Biophysics

    Structure of the human CTF18−RFC clamp loader bound to PCNA

    Giuseppina R Briola, Mohammad Tehseen ... Alfredo De Biasio
    Human CTF18–RFC employs a unique structural stabilization mechanism to optimize PCNA loading and stimulate DNA synthesis by the leading-strand polymerase.
    1. Structural Biology and Molecular Biophysics

    Multi-barrier unfolding of the double-knotted protein, TrmD–Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics

    Fernando Bruno da Silva, Szymon Niewieczerzal ... Joanna I Sulkowska
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Bifunctional Architecture Enables Substrate Catalysis and Channeling in Paracoccus TMAO Demethylase

    Trung Thach, KanagaVijayan Dhanabalan ... Ramaswamy Subramanian
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Pulsed laser lensing for phase modulation in electron microscopy

    Daniel X Du, Adam C Bartnik ... Anthony WP Fitzpatrick
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Computational and Systems Biology

    Unraveling the Molecular Mechanisms of ABHD5 Membrane Targeting

    Amit Kumar, Matthew Sanders ... Yu-ming M Huang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation

    Takashi Hotta, Morgan L Pimm ... Kristen J Verhey
    Three newly developed biosensors demonstrate that the C-terminal tail of α-tubulin does not freely extend from the microtubule surface as widely thought, but rather is inaccessible along most microtubules in cells.
    1. Structural Biology and Molecular Biophysics

    Receptor Proteins: Lipids challenge ligands to control receptors

    Adam JM Wollman
    The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.
    Version of Record
    Insight
    1. Medicine
    2. Structural Biology and Molecular Biophysics

    Medical Imaging: MRI sets its sights on collagen

    Fritz Schick
    Reducing the echo time of a whole-body MRI scanner makes it possible to image collagen, an important structural protein found in bones and tendons.
    Version of Record
    Insight
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