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    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Dock-and-lock binding of SxIP ligands is required for stable and selective EB1 interactions

    Teresa Almeida, Eleanor Hargreaves ... Igor Barsukov
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2

    Siyu Chen, Tamar Basiashvili ... Elizabeth Villa
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments

    Sofia Lövestam, Jane L Wagstaff ... Sjors HW Scheres
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Multiple modes of cholesterol translocation in the human Smoothened receptor

    Prateek D Bansal, Maia Kinnebrew ... Diwakar Shukla
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into the recruitment of viral Type 2 IRES to ribosomal preinitiation complex for protein synthesis

    Deepakash Das, Tanweer Hussain
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Structural mechanism of strand exchange by the RAD51 filament

    Luay Joudeh, Robert E Appleby ... Luca Pellegrini
    The cryoEM structure of a RAD51 displacement loop reveals the molecular mechanism of the strand-exchange reaction at the centre of eukaryotic homologous recombination.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Homologous Recombination: Snapshot of an intermediate structure

    Akira Shinohara
    Cryogenic electron microscopy has been used to determine the detailed structure of an intermediate state called a “D-loop” that forms when strands of DNA are exchanged during homologous recombination.
    Version of Record
    Insight
    1. Structural Biology and Molecular Biophysics

    Nucleosome wrapping energy in CpG islands and the role of epigenetic base modifications

    Rasa Giniūnaitė, Rahul Sharma ... Daiva Petkevičiūteė-Gerlach
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Domain coupling in allosteric regulation of SthK measured using time-resolved transition metal ion FRET

    Pierce Eggan, Sharona E Gordon, William N Zagotta
    Time-resolved fluorescence resonance energy transfer reveals conformational energetics of a bacterial cyclic nucleotide-gated ion channel.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Navigating contradictions in enteric chemotactic stimuli

    Kailie Franco, Zealon Gentry-Lear ... Arden Baylink
    Motile Enterobacteriaceae override chemorepulsion from the microbiota metabolite indole in favor of nutrient attraction, challenging the idea that indole taxis protects the host against intestinal infection.
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