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    1. Neuroscience

    Robust variability of grid cell properties within individual grid modules enhances encoding of local space

    William T Redman, Santiago Acosta-Mendoza ... Michael J Goard
    Grid cells within an individual module show significantly more variability in grid properties than would be expected by chance, resulting in improved neural representation of animal location in the environment.
    1. Plant Biology

    Systems genomics of salinity stress response in rice

    Sonal Gupta, Simon Niels Groen ... Michael D Purugganan
    Insights into the molecular and genetic landscape underlying adaptive salinity stress responses in rice.
    1. Neuroscience

    A neural network model that generates salt concentration memory-dependent chemotaxis in Caenorhabditis elegans

    Masakatsu Hironaka, Tomonari Sumi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology

    Vascular mural cells protect the adult brain from haemorrhage but do not control the blood-brain barrier in developing zebrafish

    Oguzhan F Baltaci, Andrea Usseglio Gaudi ... Benjamin M Hogan
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    SATAY-based chemogenomic screening uncovers antifungal resistance mechanisms and key determinants of ATI-2307 and chitosan sensitivity

    Matthew T Karadzas, Agnès H Michel ... Benoît Kornmann
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Pupil dilation offers a time-window on prediction error

    Olympia Colizoli, Tessa van Leeuwen ... Harold Bekkering
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Cortico-striatal action control inherent of opponent cognitive-motivational styles

    Cassandra Avila, Martin Sarter
    Electrochemical recordings of cortico-striatal glutamatergic signaling, and chemogenetic inhibition of such signaling, revealed an essential role of cortico-striatal input for cued action selection, but not for cued stopping.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state

    Ruben Sebastian-Perez, Shoma Nakagawa ... Maria Pia Cosma
    The chromatin-bound proteome of embryonic stem cells transitioning to 2C-like cells uncovers chromatin regulators involved in heterochromatin formation.
    1. Immunology and Inflammation

    Synovial macrophage diversity and activation of M-CSF signaling in post-traumatic osteoarthritis

    Alexander J Knights, Easton C Farrell ... Tristan Maerz
    Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.
    1. Computational and Systems Biology

    AI-enabled alkaline-resistant evolution of protein to apply in mass production

    Liqi Kang, Banghao Wu ... Liang Hong
    The Pro-PRIME model demonstrates the ability to engineer VHH antibody with unprecedented alkali resistance and enhanced affinity, enabling industrial applications under extreme conditions previously unattainable with natural proteins.
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