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    1. Cell Biology

    Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis

    Jingjing Li, Xinyue Wang ... Vincent Archambault
    Ankle2 functions as a regulatory subunit of PP2A and interacts with the endoplasmic reticulum protein Vap33 to promote the dephosphorylation of BAF as part of nuclear reassembly after mitosis.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    The conserved ATPase PCH-2 controls the number and distribution of crossovers by antagonizing their formation in Caenorhabditis elegans

    Bhumil Patel, Maryke Grobler ... Needhi Bhalla
    By regulating the chromosome axis component and meiotic HORMAD, HIM-3, the conserved AAA-ATPase PCH-2 controls the number and distribution of meiotic recombination events.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    The relationship between gut and nasopharyngeal microbiome composition can predict the severity of COVID-19

    Benita Martin-Castaño, Patricia Diez-Echave ... Julio Galvez
    Biomarkers of COVID-19 severity identified in nasopharyngeal and faecal microbiota could improve prognostic accuracy and treatment strategies for severe cases.
    1. Physics of Living Systems

    Stability vs flexibility: reshaping archaeal membranes in silico

    Miguel Amaral, Felix Frey ... Anđela Šarić
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Neurons in the medial prefrontal cortex that are not modulated by hippocampal sharp-wave ripples are involved in spatial tuning and signaling upcoming choice

    Hanna den Bakker, Fabian Kloosterman
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Evolutionary Biology

    Newly discovered and conserved role of IgM against viral infection in an early vertebrate

    Weiguang Kong, Xinyou Wang ... Zhen Xu
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology
    2. Immunology and Inflammation

    Clathrin-independent endocytosis and retrograde transport in cancer cells promote cytotoxic CD8 T cell activation

    Shiqiang Xu, Alix Buridant ... Henri-François Renard
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Cell Biology

    The RAB27A effector SYTL5 regulates mitophagy and mitochondrial metabolism

    Ana Lapao, Lauren Sophie Johnson ... Anne Simonsen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum

    Aske L Ejdrup, Jakob K Dreyer ... Ulrik Gether
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cancer Biology

    Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer

    Fei Yue, Amy T Ku ... Yi Li
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
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