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Synthetic polycystin proteins self-assemble as function channels when reconstituted in lipid vesicles.

Clonal naïve human embryonic stem cells assemble an Arp2/3 complex-dependent contractile actin filament ring around colonies that promotes tensional forces favoring cell-cell adhesion and nuclear translocation of YAP to maintain ground-state pluripotency.

Membrane tension controls the dynamic assembly and disassembly of caveolae and their association with the F-actin cortex in migrating cells.

Modulation of division plane rotation in proliferating chondrocytes determines the ratio of clusters and columns, which may support the multifunctional design of the growth plate.

Multiple lines of evidence demonstrate that a single N-glycan on one receptor influences the strength of a cytotoxic response elicited by natural killer cells following stimulation with an antibody-coated target.

Hepatic stellate cells play a central role in maintaining liver health by mediating cell-to-cell crosstalk via the production of GDF2 and BMP10.

Increasing adult-born neurons in the dentate gyrus reduces neuronal loss and chronic seizures in female mice using a mouse model of temporal lobe epilepsy.

There are two distinct modes of late endosome fusion in the mouse yolk sac visceral endoderm cells and actin dynamics plays a role in regulating vesicle fusion.

Long-lived tropical trees in Southeast Asia accumulate somatic mutations in a manner that is dependent on time, rather than growth rate.