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A framework for analyzing single-cell genomics data, in which geometrical properties are harnessed to obtain insights on cellular diversity, including precise clustering, clear visualizations, and intuitive diagnostics.

A new analysis method to measure the propagation of different membrane currents along complex dendritic trees reveals the conditions leading to burst firing in a computational model of place cells.

Single neurons in mouse sensorimotor cortex are organized by their activity features into distinct subpopulations with area-spanning footprints whose boundaries align closely with anatomical and somatotopic borders.

Minimally disruptive genetic code expansion enables faithful, site-specific labeling of G3BP1 and TDP-43, revealing native stress granule dynamics and ALS-linked protein behavior in live cells.

This article provides critical insights in guiding aspiring physician-scientist medical students on how to choose a clinical specialty.