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    1. Neuroscience

    Spatially targeted inhibitory rhythms differentially affect neuronal integration

    Drew B Headley, Benjamin Latimer ... Satish S Nair
    Beta and gamma inhibitory rhythms are preferentially tuned to govern synaptic integration in layer 5 pyramidal neurons by differentially modulating responses to inputs targeting distal dendritic and perisomatic compartments.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Human-specific lncRNAs contributed critically to human evolution by distinctly regulating gene expression

    Jie Lin, Yujian Wen ... Hao Zhu
    Compared with human-specific transcriptional factors, human-specific lncRNAs identified upon human lncRNAs’ orthologs in mammals have greatly evolved DNA-binding sites in archaic and modern humans in genes determining human traits.
    1. Neuroscience

    A hypothalamo-septo-hippocampal circuit for REM sleep-dependent consolidation of social memory

    Tingliang Jian, Wenjun Jin ... Han Qin
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Solid
    1. Developmental Biology
    2. Immunology and Inflammation

    HEB collaborates with TCR signaling to upregulate Id3 and enable γδT17 cell maturation in the fetal thymus

    Johanna S Selvaratnam, Juliana Dutra Barbosa da Rocha ... Michele K Anderson
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Immunology and Inflammation

    Temporal single-cell analysis reveals age-associated delay in immune resolution after respiratory viral infection

    Yue Wu, Chaofan Li ... Jie Sun
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Interaction hierarchy among Cdv proteins drives recruitment to membrane necks

    Nicola De Franceschi, Alberto Blanch-Jover, Cees Dekker
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Neural Representation of Time across Complementary Reference Frames

    Yangwen Xu, Nicola Sartorato ... Roberto Bottini
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Rescuing the Function of Missense-Mutated Tumor Suppressor VHL using Stabilizing Small Molecules

    Mariam Ahmed Fouad, Christopher S Parry ... John Karanicolas
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Audiovisual cues must be predictable and win-paired to drive risky choice

    Brett A Hathaway, Dexter R Kim ... Catharine A Winstanley
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to Plasmodium infection

    Kely C Matteucci, Nathalia PS Leite ... Ricardo T Gazzinelli
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
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