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Page 26 of 1,843
    1. Computational and Systems Biology
    2. Medicine

    Global molecular landscape of early MASLD progression in human obesity

    Qing Zhao, William De Nardo ... Philipp Kaldis
    GTPases could be drivers of liver fibrosis in MASLD and potential future therapeutic targets.
    1. Neuroscience

    Dynamic regulation of mRNA acetylation at synapses by spatial memory in mouse hippocampus

    Hai-Qian Zhou, Zhen Zhu ... Dong-Min Yin
    NAT10-mediated mRNA acetylation links neural activity to local protein synthesis at synapses, influencing memory consolidation.
    1. Microbiology and Infectious Disease

    4-Aminoquinolines block heme iron reactivity and interfere with artemisinin action

    Melissa Rosenthal, Daniel E Goldberg
    Chloroquine interferes with artemisinin activation, and such interactions should be considered when formulating antimalarial drug combinations.
    1. Physics of Living Systems

    The cytoplasm of living cells can sustain transient and steady intracellular pressure gradients

    Majid Malboubi, Mohammad Hadi Esteki ... Guillaume Charras
    Stable pressure gradients can arise in cells from the combination of actomyosin-generated cortical tension, cytoplasmic poroelasticity, and water flows across the membrane.
    1. Neuroscience

    Alcohol attenuates CRF-induced excitatory effects from the extended amygdala to dorsostriatal cholinergic interneurons

    Amanda Essoh, Xueyi Xie ... Jun Wang
    Stress-related corticotropin-releasing factor signaling directly modulates striatal cholinergic circuits, and alcohol exposure disrupts this control, revealing a circuit mechanism linking stress, alcohol use, and impaired behavioral flexibility.
    1. Genetics and Genomics
    2. Evolutionary Biology

    Mosaic of somatic mutations in one of Earth’s largest organisms, Pando

    Rozenn M Pineau, Karen E Mock ... Zachariah Gompert
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Early Sleep-Dependent Sensory Gating in the Olfactory System

    Diego Serantes, Diego Gallo ... Matías Cavelli
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Inhibitory columnar feedback neurons are involved in motion processing in Drosophila

    Miriam Henning, Madhura Ketkar ... Marion Silies
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    High frequency spike inference with particle Gibbs sampling

    Giovanni Diana, B Semihcan Sermet ... David A DiGregorio
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing