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    1. Immunology and Inflammation

    Epidermal resident memory T cell fitness requires antigen encounter in the skin

    Eric S Weiss, Toshiro Hirai ... Daniel H Kaplan
    Antigen-driven TCR signaling in the epidermis during CD8+ TRM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal TRM fitness.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Evolution of a fuzzy ribonucleoprotein complex in viral assembly

    Huaying Zhao, Tiansheng Li ... Peter Schuck
    The stability of ribonucleoprotein complexes of SARS-CoV-2 nucleocapsid proteins differs among variants of concern and the viral evolution of nucleocapsid protein can be understood in the framework of fuzzy complexes.
    1. Genetics and Genomics
    2. Medicine

    Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach

    Jacky Guy, Elena Hein ... Adrian Bird
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    The Self-Interest of Adolescents Overrules Cooperation in Social Dilemmas

    Xiaoyan Wu, Hongyu Fu ... Chao Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    The dominance of large-scale phase dynamics in human cortex, from delta to gamma

    David M Alexander, Laura Dugué
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Neuroscience

    A differentiable model for optimizing the genetic drivers of synaptogenesis

    Tommaso Boccato, Matteo Ferrante, Nicola Toschi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Ecology

    The urban tree of life: quantifying relationships between body size and urban tolerance for more than 30,000 plant and animal species

    Corey T Callaghan, Diana E Bowler ... Thomas Merckx
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling

    Stephan Tetenborg, Eyad Shihabeddin ... John O’Brien
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Continuous developmental changes in word recognition support language learning across early childhood

    Michael C Frank, Virginia A Marchman ... Martin Zettersten
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Spatial learning in multi-scale environments: Roles of hippocampus, orbitofrontal cortex, and retrosplenial cortex

    Yidan Qiu, Senning Zheng ... Ruiwang Huang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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