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    1. Cell Biology

    Extracellular vesicle-mediated release of bis(monoacylglycerol)phosphate is regulated by LRRK2 and glucocerebrosidase activity

    Elsa Meneses-Salas, Moises Castellá ... Albert Lu
    Dysregulated exocytosis of bis(monoacylglycerol)phosphate (BMP)-enriched extracellular vesicles driven by pathogenic LRRK2 activity supports elevated urinary BMP levels and its use as a biomarker for Parkinson's disease.
    1. Microbiology and Infectious Disease

    Peptidoglycan recycling is critical for cell division, cell wall integrity, and β-lactam resistance in Caulobacter crescentus

    Pia Richter, Anna Merz ... Martin Thanbichler
    Peptidoglycan recycling is essential for proper cell growth and intrinsic ampicillin resistance in Caulobacter crescentus, highlighting PG recycling enzymes as potential antibacterial targets.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Transforming a fragile protein helix into an ultrastable scaffold via a hierarchical AI and chemistry framework

    Jun Qiu, Guojin Tang ... Peng Zheng
    A hierarchical framework integrating artificial intelligence with chemical principles enables the conversion of fragile α-helices into ultrastable protein scaffolds.
    1. Neuroscience

    Dynamic modulation of social gaze by sex and familiarity in marmoset dyads

    Feng Xing, Alec G Sheffield ... Anirvan S Nandy
    A fully automated 3D tracking framework reveals that sex and familiarity strongly shape natural social gaze dynamics in freely interacting marmosets.
    1. Neuroscience

    Alpha oscillations and aperiodic neural dynamics jointly predict visual temporal resolution, confidence, and dependence on prior experience

    Gianluca Marsicano, Michele Deodato, David Melcher
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Nora virus proliferates in dividing intestinal stem cells and thereby sensitizes Drosophila flies to Pseudomonas aeruginosa intestinal infection and to oxidative stress

    Adrien Franchet, Samantha Haller ... Dominique Ferrandon
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    Opening the black box: a modular approach to spike sorting

    Samuel Garcia, Chris Halcrow ... Pierre Yger
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology

    A real-time, multi-animal model for automatic face detection and identification of freely moving common marmosets based on YOLOv8 algorithms

    Jiayue Yang, James Wang, Justine Cléry
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Visual Attention in The Fovea and The Periphery during Visual Search

    Jie Zhang, Xiaocang Zhu ... Huihui Zhou
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Representational drift under spontaneous activity - self-organized criticality enhances representational reliability

    Zhuda Yang, Junhao Liang ... Changsong Zhou
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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