Fangrui Guo, Roberto Ornelas Guevara ... Guy Tran Van Nhieu
Through low levels of extracellular ATP, EPEC induces small, rapid and coordinated Ca2+ responses in epithelial cells, a yet unreported pattern, that down-regulate inflammation at the onset of infection.
Double-knockout of PKMζ and the other atypical PKC, PKCι/λ, reveals that, without PKMζ for maintenance, PKCι/λ becomes persistently active to sustain hippocampal late-LTP and long-term memory.
Revathi Balasubramanian, Nicholas Tolman ... Simon WM John
High-resolution single-cell transcriptomics reveals the molecular programs and signaling networks driving Schlemm's canal and trabecular meshwork development, establishing a foundation for understanding glaucoma pathogenesis.
Morena Raiola, Miquel Sendra Sendra ... Miguel Torres
A computational pipeline leverages mammalian heart development videos to extract tissue deformation patterns and generate a virtual fate map tool that provides new insights into cardiac morphogenesis.