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    1. Neuroscience

    PKD2L1 channels segregated to the apical compartment are the exclusive dual-mode pH sensor in cerebrospinal fluid-contacting neurons

    Magdalena Vitar, Daniel Prieto ... Federico F Trigo
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics
    2. Neuroscience

    Integrating bulk and single cell RNA-seq refines transcriptomic profiles of individual C. elegans neurons

    Alec Barrett, Erdem Varol ... Marc Hammarlund
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    A conserved Hsp70 phosphorylation regulates cell cycle progression after DNA damage

    Thomas Moss, Alexandra Wooldredge ... Shaeri Mukherjee
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A

    Annabel Cardno, Karen Roberts, Catherine Lindon
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis

    Tongtong Xu, Fujun Cao ... Chengjian Zhao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    • Incomplete
    1. Genetics and Genomics

    A default silencing mechanism restrains stress-induced genes in C. elegans

    Orkan Ilbay, Alejandro Rodriguez Gama ... Andrew Fire
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology

    Single-Cell Characterization of Anterior Segment Development: Cell Types, Pathways, and Signals Driving Formation of the Trabecular Meshwork and Schlemm’s Canal

    Revathi Balasubramanian, Nicholas Tolman ... Simon WM John
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Immunology and Inflammation
    2. Evolutionary Biology

    Separating selection from mutation in antibody language models

    Frederick A Matsen, Will Dumm ... Hugh K Haddox
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics
    2. Medicine

    Direct MRI of Collagen

    Jason Daniel van Schoor, Markus Weiger ... Klaas Paul Pruessmann
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Chromosomes and Gene Expression

    Fragile nucleosomes are essential for RNA Polymerase II to transcribe in eukaryotes

    Lingbo Li, Samuel Hunter ... Gongyi Zhang
    Not revised
    Reviewed Preprint v1
    • Important
    • Inadequate
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