Browse our latest research

Page 27 of 1,815
    1. Genetics and Genomics

    Competition for the conserved branch point sequence influences physiological outcomes in pre-mRNA splicing

    Karen Larissa Pereira de Castro, Jose M Abril ... W Samuel Fagg
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Dissociable memory modulation mechanisms facilitate fear amnesia at different timescales

    Yinmei Ni, Ye Wang ... Jian Li
    The retrieval-extinction paradigm elicits a short-term fear amnesia that differs in cue specificity, timescale, and dependence on thought-control ability from the long-term amnesia believed to be associated with memory reconsolidation.
    1. Genetics and Genomics

    Chromatin accessibility variation provides insights into missing regulation underlying immune-mediated diseases

    Raehoon Jeong, Martha L Bulyk
    Analyzing population-level chromatin accessibility data shows added benefit over utilizing only gene expression data in elucidating the genetic mechanism of disease-associated variants.
    1. Neuroscience

    Early changes in the properties of CA3 engram cells explored with a novel viral tool in mice

    Dario Cupolillo, Noelle Grosjean ... Christophe Mulle
    A novel viral tool (FLEN) is designed, and used to monitor changes in the intrinsic and synaptic properties of engram cells quickly (3–6 hours) following encoding of a memory.
    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

    Daniel L Aldridge, Zachary Lanzar ... Christopher A Hunter
    Functional analyses showcase that in the absence of IL-27, hematopoietic stem and progenitor cells are more likely to become monocytes during toxoplasmosis, making them less responsive after infection.
    1. Neuroscience

    Spectral decomposition of local field potentials uncovers frequency-tuned gain modulation of working memory in primate visual system

    Majid Roshanaei, Mohammad Reza Daliri ... Behrad Noudoost
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    In-situ glial cell-surface proteomics identifies pro-longevity factors in Drosophila

    Madeline P Marques, Bo Sun ... Hongjie Li
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Microbiology and Infectious Disease

    The structural context of mutations in proteins predicts their effect on antibiotic resistance

    Anna G Green, Mahbuba Tasmin ... Maha R Farhat
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Lenacapavir-induced Lattice Hyperstabilization is Central to HIV-1 Capsid Failure at the Nuclear Pore Complex and in the Cytoplasm

    Arpa Hudait, Ryan C Burdick ... Gregory A Voth
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Linear and categorical coding units in the mouse gustatory cortex drive population dynamics and behavior in taste decision-making

    Liam Lang, Camelia Yuejiao Zheng ... Alfredo Fontanini
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling