Browse our latest research

Page 27 of 1,883
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Explainable machine learning-assisted exploration of chromatin dynamics reveals chromosome-specific response to serum starvation

    Taras Redchuk, Antti P Pennanen ... Maria K Vartiainen
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Medicine

    Evaluating the applicability of replication success metrics in animal-to-human translation: A simulation study

    Carolyne Jie Huang, Samuel Pawel ... Rachel Heyard
    A simulation study shows that metrics suggested to assess replication studies are useful in the translation context, but researchers need to clarify their translation goals a priori.
    1. Neuroscience

    Mood computational mechanisms underlying increased risk behavior in adolescent suicidal patients

    Zhihao Wang, Tian Nan ... Bastien Blain
    Adolescent suicidality is linked to riskier choices through stronger attraction to high-reward gambles and blunted mood responses to safe rewards.
    1. Neuroscience

    Functional specialization of mPFC-BLA and mPFC-NAc pathways in affective state representation

    Chien-Hsien Lai, Gyeongah Park ... Jianyang Du
    Separate prefrontal output channels preferentially track anxiety, exploration, and social preference, revealing how emotional context is organized into adaptive behavior.
    1. Computational and Systems Biology
    2. Stem Cells and Regenerative Medicine

    Combinatorial transcription factor interactions drive modular gene regulatory networks

    Jialei Duan, Boxun Li ... Gary C Hon
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Cancer Biology

    A Rare Nestin-Expressing Granule Cell Precursor Subpopulation Underlies SHH Medulloblastoma Formation

    Salsabiel El Nagar, Yinwen Liang ... Alexandra L Joyner
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Sequential adaptor function of Treacle and MDC1 couples nucleolar reorganization to RNF8-dependent recruitment of HDR factors

    Andrea Haenel, Johannes Leyrer ... Manuel Stucki
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Immunology and Inflammation

    Tolerance to Lung Infection in TWIK2 K+ Efflux Mediated Macrophage Trained Immunity

    Josh Thompson, Yufan Li ... Jingsong Xu
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Cell Biology

    p66Shc Mediates SUMO2-induced Endothelial Dysfunction

    Jitendra Kumar, Shravan K Uppulapu ... Santosh Kumar
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    • Solid
    1. Neuroscience

    LRRK2 regulates synaptic function through modulation of actin cytoskeletal dynamics

    Giulia Tombesi, Shiva Kompella ... Elisa Greggio
    LRRK2 couples brain-derived neurotrophic factor (BDNF) signaling to synaptic actin remodeling, defining a novel mechanism of LRRK2 synaptic function and highlighting early, targetable pathways in Parkinson’s disease.