Browse our latest research

Page 261 of 1,751
    1. Microbiology and Infectious Disease

    Rapid bacterial evaluation beyond the colony forming unit in osteomyelitis

    Qi Sun, Kimberley Huynh ... Dongqing Yang
    This time-shortened work flow improves sensitivity and specificity for the identification of bacteria in bone infections independently of bacterial culturability.
    Version of Record
    Short Report
    • Fundamental
    • Compelling
    1. Cell Biology

    Eugenol mimics exercise to promote skeletal muscle fiber remodeling and myokine IL-15 expression by activating TRPV1 channel

    Tengteng Huang, Xiaoling Chen ... Zhiqing Huang
    Eugenol has the potential as a novel exercise mimetic, and TRPV1 may represent a promising target for the development of exercise mimetics.
    1. Neuroscience

    Visuo-motor updating in individuals with heightened autistic traits

    Antonella Pomè, Eckart Zimmermann
    Efference copy dysfunctions in heightened autistic traits impair the use of eye movement information for spatial representation and object localization.
    1. Genetics and Genomics

    Discovering non-additive heritability using additive GWAS summary statistics

    Samuel Pattillo Smith, Gregory Darnell ... Lorin Crawford
    Computational analysis reveals that additive summary statistics from genome-wide association studies can provide evidence of non-additive heritability in complex traits.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Copy number variation and population-specific immune genes in the model vertebrate zebrafish

    Yannick Schäfer, Katja Palitzsch ... Jaanus Suurväli
    As a result of frequent gene duplication and haplotypic variation, a family of immune genes in the model vertebrate zebrafish has thousands of gene copies that are population- or individual-specific.
    1. Neuroscience

    Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease

    Elissavet Chartampila, Karim S Elayouby ... Helen E Scharfman
    Supplementing the diet in early life with choline improved memory, neuronal morphology, and neuronal activity in mice with a genetic form of Alzheimer's disease, whereas low choline had mixed effects.
    1. Ecology

    Coordinated molecular and ecological adaptations underlie a highly successful parasitoid

    Lan Pang, Gangqi Fang ... Jianhua Huang
    The parasitoid Trichopria drosophilae has evolved both molecular adaptions (venom proteins and teratocytes) and ecological strategies (tolerance of intraspecific and avoidance of interspecific competition) to successfully parasitize Drosophila suzukii.
    1. Structural Biology and Molecular Biophysics

    Automated multiconformer model building for X-ray crystallography and cryo-EM

    Stephanie A Wankowicz, Ashraya Ravikumar ... James S Fraser
    Creating structural models with multiple conformations of proteins improves the fit of the model to experimental data X-ray crystallography and improve the model geometry.
    1. Medicine

    Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam

    Nguyen Lam Vuong, Nguyen Than Ha Quyen ... Ronald Geskus
    Higher plasma viremia levels in early dengue and a slower subsequent decline are associated with worse clinical outcomes and provide valuable outcome measures for future therapeutic intervention trials.
    1. Developmental Biology

    The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila central nervous system

    Sanjay Kumar Sukumar, Vimala Antonydhason ... Ruth H Palmer
    The newly characterized activity regulating neuropeptide encoding gene Spar is a transcriptional target of the Jeb/Alk receptor tyrosine kinase signaling pathway in the Drosophila nervous system.