Giuseppe Deganutti, Ludovico Pipito ... Christopher Arthur Reynolds
Multiple walker supervised molecular dynamics simulations deliver insights on glucagon-like peptide 1 receptor activation, Gs protein binding, and guanosine diphosphate release from the Gsα subunit using an adaptive sampling approach.
Transcriptional regulatory network models can aid in identifying candidate genes associated with the target phenotype in bacterial genome-wide association studies.
In recurrently connected cortical networks with different inhibitory neuron subtypes, circuit modulations can increase neuronal gain without compromising network stability.
Martina Rudgalvyte, Zehan Hu ... Dominique A Glauser
Phosphoproteomics identifies diverse CaM kinase substrates, while genetic dissection reveals an unexpected antagonistic interaction with calcineurin signaling that operates in distinct neurons to regulate thermo-nociception in Caenorhabditis elegans.
