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    1. Neuroscience

    Synchronous ensembles of hippocampal CA1 pyramidal neurons during novel exploration

    En-Li Chen, Tsai-Wen Chen ... Bei-Jung Lin
    CA1 pyramidal neurons exhibit synchronous spiking during movement and pauses in novel environments, reflecting a neural signature of spatial learning.
    1. Cancer Biology

    KDM5 demethylases suppress R-loop-mediated ‘viral mimicry’ and DNA damage in breast cancer cells

    Lena Lau, Kurt Henderson ... Marie Classon
    KDM5 inhibition/disruption selectively induces R-loop-mediated DNA damage and innate immune activation in breast cancer cells, while sparing normal cells, unveiling a tumor-specific therapeutic vulnerability with broad translational potential.
    1. Cell Biology

    The RAB27A effector SYTL5 regulates mitophagy and mitochondrial metabolism

    Ana Lapao, Lauren Sophie Johnson ... Anne Simonsen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Backward Conditioning Reveals Flexibility in Infralimbic Cortex Inhibitory Memories

    Nura W Lingawi, Billy C Chieng ... Vincent Laurent
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    • Incomplete
    1. Chromosomes and Gene Expression

    Decapping activators Edc3 and Scd6 act redundantly with Dhh1 in post-transcriptional repression of starvation-induced pathways

    Rakesh Kumar, Fan Zhang ... Alan G Hinnebusch
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species

    John K Mich, Smrithi Sunil ... Boaz P Levi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Center-surround inhibition by expectation: a neuro-computational account

    Ling Huang, Shiqi Shen ... Xilin Zhang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cancer Biology

    Sex differences in bile acid homeostasis and excretion underlie the disparity in liver cancer incidence between males and females

    Megan E Patton, Sherwin Kelekar ... Sayeepriyadarshini Anakk
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Sense of control buffers against stress

    Jennifer C Fielder, Jinyu Shi ... Nikolaus Steinbeis
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Dynamic Architecture of Mycobacterial Outer Membranes Revealed by All-Atom Simulations

    Turner P Brown, Matthieu Chavent, Wonpil Im
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
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