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    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Investigation of All Disease-Relevant Lysine Acetylation Sites in α-Synuclein Enabled by Non-canonical Amino Acid Mutagenesis

    Marie Shimogawa, Ming-Hao Li ... E James Petersson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Identification and classification of ion-channels across the tree of life provide functional insights into understudied CALHM channels

    Rahil Taujale, Sung Jin Park ... Natarajan Kannan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Developmental Biology

    HSD17B7 is required for Auditory Function by Regulating Cholesterol Synthesis in Sensory Hair Cells

    Yuqian Shen, Ziyang Wang ... Dong Liu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    Genomic privacy risks in GWAS summary statistics

    Ao Lan, Yudi Pawitan, Xia Shen
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    HIV-specific CD8+ T-cell proliferative response 24 weeks after early antiretroviral therapy initiation predicts the subsequent reduction of the viral reservoir

    Pien M van Paassen, Alexander O Pasternak ... the Netherlands Cohort Study on Acute HIV Infection (NOVA) study team
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Atypical collective oscillatory activity in cardiac tissue uncovered by optogenetics

    Alexander S Teplenin, Nina N Kudryashova ... Tim De Coster
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Multi-barrier unfolding of the double-knotted protein, TrmD–Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics

    Fernando Bruno da Silva, Szymon Niewieczerzal ... Joanna I Sulkowska
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Roles of G-protein coupled receptors and mechanosensitive ion channels in pressure-induced chronotropy of lymphatic vessels

    Michael J Davis, Hae Jin Kim ... Scott D Zawieja
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    • Incomplete
    1. Developmental Biology
    2. Neuroscience

    Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function

    Caleb CS Calhoun, Mary ES Capps ... Summer B Thyme
    Sensitive brain activity mapping and behavioral profiling reveal most microexons are dispensable for early brain development but highlight a small subset with intriguing neural phenotypes for future study.
    Version of Record
    Short Report
    • Important
    • Solid
    1. Neuroscience

    Mother-child dyadic interactions shape the developing social brain and Theory of Mind in young children

    Lei Li, Jinming Xiao ... Xujun Duan
    Children’s social cognitive development emerges from the dynamic interplay of neural maturation, parental caregiving, and dyadic brain-to-brain synchrony.
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