Robert J Bastidas, Mateusz Kędzior ... Raphael H Valdivia
Genetic and biochemical analyses show that Chlamydia protects secreted effectors necessary for its exit from infected cells, preventing them from undergoing ubiquitination and degradation.
Greg J Dodge, Alyssa J Anderson ... Barbara Imperiali
Structural, functional, and bioinformatics analyses further understanding of the initial steps of prokaryotic glycoconjugate biosynthesis catalyzed by the large class of membrane-embedded monotopic phosphoglycosyl transferase superfamily.
Nikolaos Vardalakis, Amélie Aussel ... Fabien B Wagner
Combining biophysically realistic hippocampal neurons with coupled phase oscillators that represent theta inputs enables probing the phase-dependent effects of neurostimulation on theta-nested gamma oscillations in normal and pathological states.
Fission yeast loses its heterochromatin stability at mating-type locus under high temperature due to compromised binding between heterochromatin protein Swi6HP1 and Atf1.
Michael J Currie, James S Davies ... Rachel A North
Structure of the dimeric Haemophilus influenzae TRAP transporter (SiaQM) reveals two Na+ sites, the substrate-binding site and lipid-binding sites, and weak but promiscuous binding of SiaP to SiaQM.
The anti-HIV drug lenacapavir breaks the HIV capsid by stabilising regions of low curvature at the expense of maintaining a closed shell, leading to loss of viral DNA synthesis and inhibition of infection.