Nora C Brown, Benjamin Gordon ... Mariana Federica Wolfner
A functional genetics approach reveals a novel role for odorant binding proteins in post-mating processes, with complex mechanisms of evolutionary change across closely related insect species.
Reto B Cola, Diana M Roccaro-Waldmeyer ... Marco R Celio
Foxb1-expressing hypothalamic neurons in the parvafox nucleus and the dorsal premammillary nucleus both contribute to behavioral and physiological components associated with defensive behavior.
Real-time visualization of Salmonella enterica and polarized macrophage interaction in the living host identifies an anti-inflammatory, pro-regenerative, and motionless macrophage subset as a survival niche during persistent infection.
The PrEDiCT scheme infers disease-affected cell types from the expression of disease-associated genes in single-cell expression atlases, thereby providing cellular context and enhancing mechanistic understanding for 328 Mendelian diseases.
Salman Shehzada, Tomoko Noto ... Kazufumi Mochizuki
The identification of a SUMO E3 ligase engaged in lncRNA transcription, subsequently leading to target-directed small RNA degradation, reveals an unexplored layer of regulatory mechanisms within small RNA-directed chromatin regulation.
Andrew T Lombardo, Cameron AR Mitchell ... Anthony Bretscher
ARHGAP18 specializes in controlling cell shape at the topmost layer of the cell membrane by regulating the interaction between the ERM protein family, RhoA signaling, and the actin cytoskeleton.
A computational method has been developed for predicting the cell-type-specific binding of transcription factors to nucleosomes, and involves integration of ChIP-seq, MNase-seq, and DNase-seq data with details of nucleosome structure.
Carla de la Fuente, Alexandre Grondin ... Laurent Laplaze
Increased primary root growth in pearl millet is correlated with early water stress tolerance, an important constraint in agrosystems in the Sahel, and is associated with the regulation of root cell elongation by a glutaredoxin.
Sebastian Pöhl, Manuel Osorio-Valeriano ... Martin Thanbichler
Analyses of the stalked budding bacterium Hyphomonas neptunium and its spiral-shaped relative Rhodospirillum rubrum reveal a conserved morphogenetic module that controls the establishment of complex bacterial cell shapes.
