Browse our latest research

Page 398 of 1,811
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    The bile acid receptor TGR5 regulates the hematopoietic support capacity of the bone marrow niche

    Alejandro Alonso-Calleja, Alessia Perino ... Olaia Naveiras
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    The involvement of the human prefrontal cortex in the emergence of visual awareness

    Zepeng Fang, Yuanyuan Dang ... Mingsha Zhang
    While minimizing the report-related motor confounding, event-related potential (ERP), high-frequency power, and functional connectivity of the local field potential (LFP) activity in human prefrontal cortex were enhanced under the emergence of visual awareness.
    1. Genetics and Genomics

    Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo

    Swati Gaikwad, Fardin Ghobakhlou ... Alan G Hinnebusch
    Eliminating eukaryotic initiation factor 2 (eIF2) from wild-type budding yeast had little impact on translation of individual mRNAs, including those with regulatory upstream open-reading frames, even when canonical initiation factor eIF2 activity was impaired.
    1. Cell Biology

    Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

    Yin Luo, Huanmeng Hao ... Ding Xu
    By binding to TRAIL and inducing its oligomerization, heparan sulfate plays a role in regulating the pro-apoptotic activity of TRAIL towards several types of tumor cells.
    1. Cell Biology
    2. Developmental Biology

    Dally is not essential for Dpp spreading or internalization but for Dpp stability by antagonizing Tkv-mediated Dpp internalization

    Niklas Simon, Abu Safyan ... Shinya Matsuda
    The heparan sulfate chains of the glypican Dally stabilizes morphogen Dpp on the cell surface by antagonizing receptor-mediated Dpp internalization largely independent of direct interaction with Dpp.
    1. Evolutionary Biology

    Measures of genetic diversification in somatic tissues at bulk and single-cell resolution

    Marius E Moeller, Nathaniel V Mon Père ... Weini Huang
    Single-cell and bulk sequencing data are combined through theoretical modeling to reveal the number of tissue-specific stem cells, mutation, and proliferation rates under sampling.
    1. Neuroscience

    Passive exposure to task-relevant stimuli enhances categorization learning

    Christian Schmid, Muhammad Haziq ... Santiago Jaramillo
    Mice learn a categorization task faster when exposed to task-relevant stimuli outside training, supporting neural-network models in which unsupervised learning first captures the statistical structure of inputs before classifying them.
    1. Genetics and Genomics
    2. Neuroscience

    The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics

    Lukas M Weber, Heena R Divecha ... Stephanie C Hicks
    Spatially-resolved transcriptomics and single-nucleus RNA-sequencing are applied to the human locus coeruleus to characterize the gene expression profiles of norepinephrine (NE) neurons and other cell populations in this critical brain region, with all data made publicly available.
    1. Microbiology and Infectious Disease

    Physiological and metabolic insights into the first cultured anaerobic representative of deep-sea Planctomycetes bacteria

    Rikuan Zheng, Chong Wang ... Chaomin Sun
    A deep-sea Planctomycetes bacterium performs a unique budding mode of division and recruits chronic phages for metabolizing nitrogen through the function of auxiliary metabolic genes.
    1. Evolutionary Biology
    2. Medicine

    Taste shaped the use of botanical drugs

    Marco Leonti, Joanna Baker ... Julie Hawkins
    Plant drugs used by ancient Graeco-Roman societies have tastes and flavours that predict how they were used therapeutically.