Harsh N Hariani, A Brynn Algstam ... Timothy S Balmer
Unipolar brush cells subtypes, classified by their excitatory or inhibitory response to glutamate, form circuits with one another that may enhance the capacity of the cerebellum to transform input signals.
Unveiling the high-confidence protein–protein interaction networks of human and fly α-arrestins provides insights into conserved and species-specific functional roles depending on their protein domains and motifs.
Clare Andradi-Brown, Jan Stephan Wichers-Misterek ... Anna Bachmann
An enhanced bioinformatic pipeline to quantify Plasmodium falciparum core gene and polymorphic var gene expression revealed changes occurring during early culture adaptation of parasites from naturally infected individuals.
Nathan Tague, Cristian Coriano-Ortiz ... Mary J Dunlop
The LOVdeg tag is a versatile tool for bacterial optogenetics, offering modular, blue light-inducible protein degradation for a range of synthetic biology and metabolic engineering applications.
Jesus A Castor-Macias, Jacqueline A Larouche ... Carlos A Aguilar
The treatment of injury from volumetric muscle loss with Maresin 1 reduces inflammation and fibrosis, driving improvements in the recovery of muscle strength.
Xingyu Ding, Sean Froudist-Walsh ... Xiao-Jing Wang
Large-scale modeling of the mouse brain revealed that working memory is modular and determined by long-range cell type-specific connections, thereby providing a framework to interpret brain-wide recordings during cognition.
Ruth Charlotte Eccleston, Emilia Manko ... Nicholas Furnham
A computational method for predicting evolutionary pathways to antimicrobial resistance, accounting for how epistatic interactions determine trajectories, is described.