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The α₁-adrenergic receptor augments the activity of the L-type Ca²⁺ channel Ca_V1.2 through PKC and the tyrosine kinases Pyk2 and Src and thereby synaptic plasticity.

Overlapping DNA-binding specificity allows global transcription factors to cooperatively bind the same DNA sites and integrate two signals in the control of gene expression.

Recurrent neural networks trained to navigate and infer latent states exhibit strikingly similar remapping patterns to those observed in navigational brain areas, inspiring new analyses of published data and suggesting a possible function for spontaneous remapping to support context-dependent navigation.

Connectomics of the octopus 'fan-out fan-in’ learning network reveals that the intermediate layer uses approximately 22×10⁶ excitatory interneurons, each can store a single sensory input, while approximately 400×10³ integrating inhibitory interneurons adjust the network output level.

Genetic, phenotypic, and evolutionary analysis of a clinical isolate provides an explanation of the intricate genetic factors behind non-carbapenemase carbapenem resistance and sheds light on the evolutionary mechanisms that influence the molecular basis of antibiotic resistance.

Zebrafish are an optimal model organism to study rare TP53 mutations whose functions are not readily understood.

Definitions of reproducibility vary considerably across disciplines and overall rates of reproducibility are low irrespective of the definition used.

Biochemical and cell biology studies reveal that postsynaptic density condensates of neuronal synapses and actin cytoskeletons can directly communicate with each other in a phase separation-dependent manner.

Discovery of a rapidly spreading outbreak of bacterial blight in Tanzania caused by a Xanthomonas strain that originates from Asia and editing of Komboka rice lines resistant to the newly introduced strains and to other Asian and African strains.