Browse our latest research

Page 50 of 1,887
    1. Biochemistry and Chemical Biology

    ᴅ-serine suppresses one-carbon metabolism by competing with mitochondrial ʟ-serine transport

    Masataka Suzuki, Kenichiro Adachi ... Jumpei Sasabe
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Medicine

    Estimating bone marrow adiposity from head MRI and identifying its genetic architecture

    Tobias Kaufmann, Pål Marius Bjørnstad ... Timothy Hughes
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology

    Large-scale synthetic data enable digital twins of human excitable cells

    Pei-Chi Yang, Mao-Tsuen Jeng ... Colleen E Clancy
    Large-scale synthetic datasets enable construction of digital twins of individual human excitable cells from a single voltage-clamp recording.
    1. Structural Biology and Molecular Biophysics

    Structural dynamics of IRE1 and its interaction with unfolded peptides

    Elena Spinetti, Grzegorz Ścibisz ... Roberto Covino
    A unified structural model of IRE1 activation reconciles conflicting sensing theories by characterizing specific peptide-binding sites and the mechanism by which BiP regulates oligomerization during the unfolded protein response.
    1. Evolutionary Biology

    The population structure of invasive Lantana camara is shaped by its mating system

    P Praveen, Rajesh Gopal, Uma Ramakrishnan
    Invasive Lantana camara exhibits strong genetic structure, unlike many invasive species, likely driven by predominant self-fertilization across its invasive range rather than the presence of multiple species.
    1. Computational and Systems Biology

    Functional muscle networks as biomarkers of post-stroke motor impairment and therapeutic responsiveness

    David O'Reilly, Giorgia Pregnolato ... Giacomo Severini
    The proposed muscle network analysis framework identifies a redundancy-to-synergy shift as a marker of stroke recovery, yielding new biomarkers that could objectively quantify functional impairment and rehabilitation efficacy.
    1. Neuroscience

    Zapit: Open Source Laser-Scanning Photostimulation For Neuroscience

    Michael Lohse, Oliver M Gauld ... Robert AA Campbell
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology

    Identification of key Y4R residues enables the discovery of selective non-peptide small-molecule agonists

    Tim Pelczyk, Corinna Schüß ... Annette G Beck-Sickinger
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Physiology

    Aging induced structural alterations in SR-Mitochondria interaction in skeletal muscle: Emerging insights

    Unmod Senapati, Barsha Priyadarshini Kar ... Naresh Chandra Bal
    Not revised
    Reviewed Preprint v1
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Enteropathogenic Escherichia coli-mediated fast and coordinated Ca²+ responses regulate NF-κB activation

    Fangrui Guo, Roberto Ornelas Guevara ... Guy Tran Van Nhieu
    Through low levels of extracellular ATP, EPEC induces small, rapid and coordinated Ca2+ responses in epithelial cells, a yet unreported pattern, that down-regulate inflammation at the onset of infection.