A novel form of collective mesenchymal cell migration is identified during chick gastrulation, where a dynamic 3D meshwork supported by N-cadherin-mediated adhesion coordinates movement and enhances directional migration in the unconfined space between ectoderm and endoderm.
Full-length, autoinhibited LRRK2 assembles into distinct, shorter microtubule-bound filaments via a previously unobserved N-terminal repeat interface, revealing new structural states with potential therapeutic implications.
Protein–protein interactions and localization dependencies between septin cytoskeleton and the exocyst complex using the fission yeast model system reveal one of the most conserved functions of septins in exocytosis.
A distinct subset of leaf companion cells expresses high levels of the florigen gene, and the same cells also produce other possible mobile floral regulators and small proteins.
OpenSpliceAI is an open, retrainable framework for splice site prediction that enables rapid, memory-efficient, cross-species analyses at scale with accuracy comparable to SpliceAI.
