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    1. Computational and Systems Biology

    Anatomical basis of sex differences in the electrocardiogram identified by three-dimensional torso-heart imaging reconstruction pipeline

    Hannah J Smith, Blanca Rodriguez ... Abhirup Banerjee
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Incomplete
    1. Neuroscience

    Overt visual attention modulates decision-related signals in ventral and dorsal medial prefrontal cortex

    Blair RK Shevlin, Rachael Gwinn ... Ian Krajbich
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Sibling chimerism among microglia in marmosets

    Ricardo CH del Rosario, Fenna M Krienen ... Steven A McCarroll
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    In vitro reconstitutions suggest a general model for paradoxical activation of ARAF, BRAF, and CRAF by diverse RAF inhibitor types that does not rely on negative allostery

    Emre Tkacik, Dong Man Jang ... Michael J Eck
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology
    2. Genetics and Genomics

    Temporally controlled nervous system-to-gut signaling bidirectionally regulates longevity in C. elegans

    Lingxiu Xu, Chengxuan Han ... Jianfeng Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cancer Biology

    Design of combination therapeutics from protein response to drugs in ovarian cancer cells

    Alexandra Franz, Ciyue Shen ... Chris Sander
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Medicine

    Single transcript level atlas of oxytocin and the oxytocin receptor in the mouse brain

    Vitaly Ryu, Anisa Azatovna Gumerova ... Mone Zaidi
    The compendium of oxytocin and its receptor in the brain could provide further insights into the peripheral and central effects of oxytocin in health and disease.
    1. Neuroscience

    Dynamic regulation of mRNA acetylation at synapses by spatial memory in mouse hippocampus

    Hai-Qian Zhou, Zhen Zhu ... Dong-Min Yin
    NAT10-mediated mRNA acetylation links neural activity to local protein synthesis at synapses, influencing memory consolidation.
    1. Physics of Living Systems

    The cytoplasm of living cells can sustain transient and steady intracellular pressure gradients

    Majid Malboubi, Mohammad Hadi Esteki ... Guillaume Charras
    Stable pressure gradients can arise in cells from the combination of actomyosin-generated cortical tension, cytoplasmic poroelasticity, and water flows across the membrane.
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    Superoxide dismutases maintain niche homeostasis in stem cell populations

    Olivia Majhi, Aishwarya Chhatre ... Devanjan Sinha
    Superoxide dismutases, particularly Sod1, differentially tune redox signaling of germline and cyst stem cells, enabling their self-renewal and differentiation, thereby maintaining Drosophila testicular stem cell homeostasis.
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