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    1. Evolutionary Biology
    2. Immunology and Inflammation

    Heterozygote advantage cannot explain MHC diversity, but MHC diversity can explain heterozygote advantage

    Joshua L Cherry
    The unusually high genetic diversity of MHC genes cannot be explained by heterozygote advantage alone because heterozygote advantage is not expected without some other driver of diversity.
    1. Developmental Biology

    Gcn5 – mTORC1 – TFEB signalling axis mediated control of autophagy regulates Drosophila blood cell homeostasis

    Arjun Aji Reeja, Mincy Kunjumon ... Rohan Jayant Khadilkar
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cancer Biology

    PCNA-Polκ-Polδ/USP18 axes stabilize replication fork and restart to reduce cisplatin cytotoxicity

    Ipsita Subhadarsini, Jugal Kishor Sahu ... Narottam Acharya
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Cooperative antibiotic response in coupled biofilm and planktonic E. faecalis communities

    Gabriela Fernandes Martins, Keanu Alexander Guardiola-Flores ... Kevin Wood
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Astrocytic Nonsense-mediated mRNA decay regulates calcium signaling to support synapse function and restrain anxiety

    Pablo J Lituma, Aykut Deveci ... Dilek Colak
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Neuroscience

    Primate Hippocampus Reveals Distinct Rules for Associative Synaptic Plasticity

    Anoop Manakkadan, Krishna Kumar ... Sreedharan Sajikumar
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Congenital aphantasia reveals frontotemporal and cingulate structural alterations underlying conscious access to imagery

    Yusaku Takamura, Romain Delsanti ... Jianghao Liu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Nanoscale organization of betaII-spectrin within segments of the membrane-associated periodic skeleton in mouse sciatic nerve axons

    Nahir Guadalupe Gazal, Gonzalo Escalante ... Nicolás Unsain
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Estimating the replicability of Brazilian biomedical science

    The Brazilian Reproducibility Initiative
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Anterior cingulate cortex monitors action state and action content in complex associative learning

    Wenqiang Huang, Arron F Hall ... Dong V Wang
    ACC contains specialized neurons that sustain rich action-relevant information after action execution, enabling prolonged action monitoring, and supporting complex associative linking across events.
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