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    1. Cancer Biology

    Identifying tissue states by spatial protein patterns related to chemotherapy response in triple-negative breast cancer

    Luciana M Luque, Mohammad Asif Khan ... Linus J Schumacher
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    A rapid transfer of virions coated with heparan sulfate from the ECM to CD151 defines an early step in the human papillomavirus infection cascade

    Annika Massenberg, Yahya Homsi ... Thorsten Lang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β

    Kanako Shinno, Yuri Miura ... Kanae Ando
    Upregulation of the β subunit of translation initiation factor eIF2 underlies autophagy suppression and premature aging caused by disruption of axonal transport of mitochondria.
    1. Biochemistry and Chemical Biology

    Phenylhydrazone-based endoplasmic reticulum proteostasis regulator compounds with enhanced biological activity

    Gabriel M Kline, Lisa Boinon ... R Luke Wiseman
    Establishment of AA263 analogs with improved potential for correcting pathologic disruptions of endoplasmic reticulum proteostasis implicated in the onset and pathogenesis of etiologically diverse diseases.
    1. Neuroscience

    Sex-specific exploration accounts for differences in valence learning in male and female mice

    Heike Schuler, Eshaan S Iyer ... Rosemary C Bagot
    Deep behavioral phenotyping reveals that performance readouts from single-valence conditioning are biased by baseline sex differences in exploration, and mixed-valence conditioning provides a clearer assessment of learning in both sexes.
    1. Neuroscience

    Spontaneous fluctuations in global connectivity reflect transitions between states of high and low prediction error

    Paul C Bogdan, Shenyang Huang ... Roberto Cabeza
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Multi-talker speech comprehension at different temporal scales in listeners with normal and impaired hearing

    Jixing Li, Qixuan Wang ... Zhiwu Huang
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    Activation of the Spx redox sensor counters cysteine-driven Fe(II) depletion under disulfide stress

    Abigail G Hall, Abdulelah A Alqarzaee ... Vinai C Thomas
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Chromosomes and Gene Expression

    Impacts of DNA Methylation on H2A.Z Deposition and Nucleosome Stability

    Rochelle M Shih, Yasuhiro Arimura ... Hironori Funabiki
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Neuroscience

    Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum

    Aske Ejdrup, Jakob Kisbye Dreyer ... Ulrik Gether
    A computational model of the striatal dopamine system predicts transporter expression and organisation as key determinants of regional striatal dopamine dynamics and distinct signal decoding by D1 and D2 receptors.
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