Modestas Matusevicius, Robin A Corey ... Simone Weyand
Cryo-EM structures of human aquaporin AQP2 bound to the anti-trypanosomal drugs pentamidine and melarsoprol identify the molecular mechanism for drug-resistant sleeping sickness.
A context-driven memory model simulates a wide range of characteristics of waking and sleeping hippocampal replay, providing a new account of how and why replay occurs.
Exosome-associated THSD7A is identified as a key trigger of filopodia formation in cancer cells and neurons, revealing a novel pathway with implications for metastasis, neuronal connectivity, and other filopodia-dependent processes.
Genetic perturbation of Afadin in the retina reveals its importance for the precise organization of the retinal layers while leaving neuronal fate and numbers unaffected.