Browse our latest research

Page 50 of 1,804
    1. Cell Biology
    2. Medicine

    Uncovering Shared and Tissue-Specific Molecular Adaptations to Intermittent Fasting in Liver, Brain, and Muscle

    Yibo Fan, Senuri De Silva ... Thiruma V Arumugam
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    Stall force measurement of the kinesin-3 motor KIF1A using a programmable DNA origami nanospring

    Nobumichi Takamatsu, Hiroko Furumoto ... Kumiko Hayashi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Plant Biology

    Structure-guided secretome analysis of gall-forming microbes offers insights into effector diversity and evolution

    Soham Mukhopadhyay, Muhammad Asim Javed ... Edel Perez-Lopez
    Comparative structural genomics identifies unique effector architectures and ankyrin-mediated host targeting, revealing central and conserved strategies that underpin the pathogenicity of diverse gall-forming microbial species across evolutionary lineages.
    1. Physics of Living Systems

    Balancing stability and flexibility when reshaping archaeal membranes

    Miguel Amaral, Felix Frey ... Anđela Šarić
    Archaeal cells mix single-headed and double-headed lipids to construct resilient but flexible membranes to help them survive in extreme environments.
    1. Neuroscience

    Distributed subthreshold representation of sharp wave-ripples by hilar mossy cells

    Ayako Ouchi, Taro Toyoizumi ... Yuji Ikegaya
    Machine learning with whole-cell patch-clamp and local field potential recordings reveals that synaptic responses from five mossy cells, despite their limited population, can significantly reconstruct about 30% of the total hippocampal sharp wave-ripples, highlighting efficient distributed coding within subthreshold activities.
    1. Neuroscience

    Social experience shapes fighting strategies in Drosophila

    Can Gao, Mingze Ma ... Yufeng Pan
    Social enrichment increases the less-frequent high-intensity aggressive tussling and decreases the low-intensity aggressive lunging via distinct sensory and central neurons.
    1. Structural Biology and Molecular Biophysics

    DIRseq as a method for predicting drug-interacting residues of intrinsically disordered proteins from sequences

    Matt MacAinsh, Sanbo Qin, Huan-Xiang Zhou
    A sequence-based method, DIRseq, has been developed to predict drug-interacting residues of intrinsically disordered proteins.
    1. Developmental Biology

    Distinct waves of ovarian follicles contribute to mouse oocyte production

    Qi Yin, Allan C Spradling
    The first follicle wave undergoes atresia to amplify androgen-producing theca cells, while previously unknown wave 1.5 follicles leave quiescence at 2 weeks and produce most of the earliest offspring.
    1. Neuroscience

    A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex

    Cecilia Hes, Abigail J Tomlinson ... Paul V Sabatini
    The dorsal vagal complex is a highly intricate structure composed of distinct transcriptional classes of glial and neuronal cells, exhibiting many similarities but also notable differences between mice and rats.
    1. Neuroscience

    Two classes of amine/glutamate multi-transmitter neurons innervate Drosophila internal male reproductive organs

    Martha Chaverra, John Paul Toney ... R Steven Stowers
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing