Nooshin Sheidaei, John K Eykelenboom ... Tomoyuki U Tanaka
An actomyosin network (PANEM) forms around the nucleus in prophase, and its contraction repositions peripheral and polar chromosomes to facilitate their interaction with the mitotic spindle, ensuring their correct segregation.
Katie H Long, Emily E Fitzgerald ... Charles M Greenspon
The breast, despite its importance in sexual and affective touch, exhibits poor tactile localization and demonstrates a relationship between size and innervation density.
Evgeny Zatulovskiy, Magdalena B Murray ... Jan M Skotheim
Cellular sensitivity to cell death stimuli depends on cell-size-dependent proteome changes - specifically, cell size can modulate ferroptosis susceptibility through changes in glutathione biosynthetic enzymes, ferritin, and cathepsin B concentrations.
A comprehensive mutational scan of TYK2 identifies novel allosteric sites, elucidates functional drug-protein interactions, and links autoimmune disease protection to reduced TYK2 protein abundance.
Sophie Hall, Iara Aime Cardoso ... Christiane Schaffitzel
A generic strategy for producing functional snake venom metalloproteinases opens the field to reproducible mechanistic studies and inhibitor discovery.
