Megan E Patton, Sherwin Kelekar ... Sayeepriyadarshini Anakk
Transcriptomic and metabolite analysis reveal sex differences in circulation and excretion of bile acids in a mouse- model of hepatocellular carcinoma (HCC), and the identified female-specific gene profile correlates with better HCC survival.
Jakob Cronshagen, Johannes Allweier ... Tobias Spielmann
The generation of malaria parasites expressing only one of the multiple variants of their most important virulence factor enables the study of different aspects of this virulence factor.
Maintaining CDK4/6 inhibition constrains drug‑resistant breast tumors by delaying cell‑cycle entry, and adding CDK2 inhibition further deepens control to guide post‑progression therapy.
ANKEF1 stabilizes the sperm axoneme by reinforcing the nexin–dynein regulatory complex, revealing a mechanical buffering mechanism essential for flagellar integrity and male fertility.
R Sai Prathap Yadav, Paulami Dey ... Pavan Agrawal
A low-cost, portable platform combining machine learning–based classifiers enables accurate quantification of Drosophila aggression and courtship, expanding access to behavioral neuroscience in resource-limited settings.
Increased fucosylated IgG and reduced bisecting GlcNAc during HTNV convalescence may promote rapid recovery from hemorrhagic fever with renal syndrome.
Physical gel models and numerical simulations have been created to study ferret brain gyrification and cortical malformations, while comparisons with human phenotypes aim to link genetics and brain morphogenesis.
Conan JO O'Brien, Giorgio Ratti ... Ana I Domingos
Loss of class A scavenger receptor MARCO results in elevated lung Ace expression and elevated plasma aldosterone concentrations in male mice, demonstrating an endocrine function of this immune scavenger receptor.
