Genetic analyses in budding yeast coupled with biochemical assays have revealed an unexpected role for the Smc5/6 complex in cellular pathways responsible for the prevention of RNA formation in genomic DNA.
Clara Bekirian, Isabel Valsecchi ... Thierry Fontaine
β-1,6-Glucan is crucial for Candida albicans cell wall structure and integrity, adapting dynamically to environmental stresses and compensating for mannan deficiencies in cell wall organization.
Santiago Otero-Coronel, Thomas Preuss, Violeta Medan
Multisensory enhancement of Mauthner cell activity reveals how stimulus modality, intensity, and temporal dynamics shape integration at the single-cell level in a neuron essential for fast escape responses.
Molecular genetics identifies a novel microglial pathway essential for mouse brain development and a previously unknown anti-inflammatory activity of monomeric amyloid β that activates this pathway.
A revised analytical framework grounded in the principle of binomial distribution captures the full clonality and dynamic shifts of hematopoiesis throughout ontogeny.
