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Page 510 of 1,838
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Intestinal GCN2 controls Drosophila systemic growth in response to Lactiplantibacillus plantarum symbiotic cues encoded by r/tRNA operons

    Théodore Grenier, Jessika Consuegra ... François Leulier
    Bacterial ribosomal and transfer RNAs are symbiotic clues sensed by host general control nonderepressible 2 to support Drosophila systemic growth.
    1. Cell Biology
    2. Computational and Systems Biology

    An in silico FSHD muscle fiber for modeling DUX4 dynamics and predicting the impact of therapy

    Matthew V Cowley, Johanna Pruller ... Christopher RS Banerji
    Mathematical and experimental characterization of DUX4 expression dynamics in facioscapulohumeral muscular dystrophy muscle fibers, provides insights into pathology and open-source tools for in silico investigation of anti-DUX4 therapy.
    1. Developmental Biology
    2. Neuroscience

    Glial-dependent clustering of voltage-gated ion channels in Drosophila precedes myelin formation

    Simone Rey, Henrike Ohm ... Christian Klämbt
    Evolution of saltatory conductance is mirrored in fly development where glia-dependent clustering of voltage-gated ion channels precedes myelination.
    1. Ecology

    Divergent functions of two clades of flavodoxin in diatoms mitigate oxidative stress and iron limitation

    Shiri Graff van Creveld, Sacha N Coesel ... E Virginia Armbrust
    Diatoms encode two forms of flavodoxin with divergent functions that mitigate the oxidative stress and iron requirements associated with life in contemporary oxygenated iron-poor oceans.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Haploinsufficiency of the essential gene Rps12 causes defects in erythropoiesis and hematopoietic stem cell maintenance

    Virginia Folgado-Marco, Kristina Ames ... Nicholas E Baker
    The homozygous and heterozygous phenotypes of mouse Rps12 deletion are described, highlighting pancytopenia reflecting roles in hematopoiesis and erythropoiesis.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cell-free DNA as a potential biomarker of differentiation and toxicity in cardiac organoids

    Brian Silver, Kevin Gerrish, Erik Tokar
    Cardiac organoids have potential as a tool used for identifying cell-free DNA as biomarkers for toxicity and severity of exposure outcomes.
    1. Neuroscience

    Distinct hippocampal and cortical contributions in the representation of hierarchies

    Robert Scholz, Arno Villringer, Mauricio J.D. Martins
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Cancer Biology

    Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development

    Robbin A. Nameki, Heidi Chang ... Kate Lawrenson
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Biochemistry and Chemical Biology

    Nuclear bodies protect phase separated proteins from degradation in stressed proteome

    Kwan Ho Jung, Jiarui Sun ... Xin Zhang
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Incomplete
    1. Neuroscience

    The impact of task context on predicting finger movements in a brain-machine interface

    Matthew J Mender, Samuel R Nason-Tomaszewski ... Cynthia A Chestek
    Task changes, like increased force production or altered posture, decrease the accuracy of brain-machine interfaces predicting intended finger movements, however, understanding how neural activity changes with the altered biomechanics of the task may provide insights for generalizable decoder development.