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DCX negatively regulates dynein-mediated retrograde transport through two critical interactions by regulating dynein binding to microtubules and regulating the composition of dynein/dyactin/JIP3 motor complex.

Human thalamic activity transformed via thalamocortical functional connectivity to support task representations across functional domains.

LncRNA Neat1, with paraspeckle proteins, controls translational induction of (lymph)angiogenic and cardioprotective factors by the IRES-dependent mechanism in mouse cardiomyocytes submitted to hypoxia.

The southern house mosquito senses the oviposition attractants skatole and indole with two receptor proteins sharing only 50% amino acid identity, and having the residues alanine-73 and leucine-74 in the skatole and indole receptors, respectively, control their specificity.

Pairs of spinal cord neurons arising from a shared progenitor get input from and make outputs to mostly different synaptic partners.

A mechanism is proposed that allows investigators to study interventions to delay onset of heart disease in patients suffering from chronic inflammatory disease with bone loss.

Laser trap measurements show that mechanical work output from curling protofilaments is enhanced by adding magnesium, and that yeast microtubules generate larger and more energetic working strokes than bovine microtubules.

The localization of Rad53 cell cycle checkpoint kinase to many gene promoters and the dynamic changes in response to replication stress suggests that the kinase may coordinate genome stability and gene expression.

In vitro assays using Xenopus egg extracts provide evidence that mitosis-specific loading of condensin I is accelerated by phosphorylation of the N-terminal tail of its kleisin subunit.

Mouse deficiencies for the dynein-binding protein LIS1 reveal different cell division mechanisms across T-cell subsets.