Browse our latest research

Page 559 of 1,760
    1. Neuroscience

    Robust cone-mediated signaling persists late into rod photoreceptor degeneration

    Miranda L Scalabrino, Mishek Thapa ... Greg D Field
    The retina compensates for rod death and deteriorating cones to retain high-fidelity visual signaling to the brain.
    1. Epidemiology and Global Health

    Linking rattiness, geography and environmental degradation to spillover Leptospira infections in marginalised urban settings: An eco-epidemiological community-based cohort study in Brazil

    Max T Eyre, Fábio N Souza ... Federico Costa
    While flooding events may drive spillover transmission of Leptospira spp. through dispersal of the bacteria at low elevations, at higher elevations environmental risk is more localised and directly driven by the distribution of local rat reservoir populations.
    1. Immunology and Inflammation

    The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function

    Shasha Li, Michael D Bern ... Wayne M Yokoyama
    Deficiency of the transcriptional repressor, Bach2, results in more mature mouse natural killer cells.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The wtf meiotic driver gene family has unexpectedly persisted for over 100 million years

    Mickaël De Carvalho, Guo-Song Jia ... Sarah E Zanders
    The wtf family of meiotic drivers has maintained the capacity to cause meiotic drive for over 100 million years.
    1. Neuroscience

    Uncertainty-based inference of a common cause for body ownership

    Marie Chancel, H Henrik Ehrsson, Wei Ji Ma
    Behavioral and computational results show that the perception of our body as our own depends on Bayesian probabilistic reasoning that take into account the variations in sensory uncertainty when integrating visual and somatosensory cues.
    1. Neuroscience

    Stability of motor representations after paralysis

    Charles Guan, Tyson Aflalo ... Richard A Andersen
    Neural populations in PPC dynamically represent motor-like and then sensory-like aspects of brain–computer interface finger movements with a representational structure that matches able-bodied individuals.
    1. Developmental Biology
    2. Genetics and Genomics

    Variable paralog expression underlies phenotype variation

    Raisa Bailon-Zambrano, Juliana Sucharov ... James T Nichols
    Within populations, there is standing variation in paralog expression levels, paralog expression levels are heritable, and variation in paralog expression can modify the phenotypes associated with mutation of one of the paralogs.
    1. Neuroscience

    Flexing the principal gradient of the cerebral cortex to suit changing semantic task demands

    Zhiyao Gao, Li Zheng ... Elizabeth Jefferies
    Gradient decomposition of informational connectivity reveals that the principal gradient with the separation of default mode network from sensory-motor systems represents a hallmark of the retrieval of strong conceptual links.
    1. Immunology and Inflammation

    Bronchus-associated macrophages efficiently capture and present soluble inhaled antigens and are capable of local Th2 cell activation

    Xin-Zi Tang, Lieselotte S M Kreuk ... Christopher D C Allen
    Lung interstitial macrophages are strategically positioned underneath the bronchial airway epithelium and enriched at airway bifurcations for immunosurveillance of the conducting airway lumen and the initiation of adaptive immune responses.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Rapid, Reference-Free human genotype imputation with denoising autoencoders

    Raquel Dias, Doug Evans ... Ali Torkamani
    A new autoencoder-based genotype imputation method shows superior accuracy across human genomes of diverse ancestry and across the allele-frequency spectrum, while delivering significantly faster inference run times relative to standard imputation tools.