Browse our latest research

An individual-specific gene interaction perturbation network-based (GIN) approach reveals six stable GIN subtypes (GINS1-6) with distinguishing and high-resolution features.

Mitochondrial Cx43 hemichannels regulate ATP generation by mediating K+, H+, and ATP transfer across the mitochondrial inner membrane and the interaction with mitochondrial ATP synthase, contributing to maintenance of mitochondrial redox and cell protection under oxidative stress.

Coarse-grained modeling of mammalian kinetochore-fiber shapes generated under microneedle manipulation reveals the need for lateral anchorage 1-3 μm from the kinetochore to robustly preserve their orientation in the spindle center, promoting mechanical integrity in the dynamic spindle.

The rodent brain represents uncertainty associated with short-term predictions during naturalistic navigation tasks sequentially by sampling hypothetical future trajectories in every ~100 ms, corresponding to successive theta cycles.

The capacity to sustain effort to obtain rewards over time depends on the levels of the antioxidant glutathione in the nucleus accumbens - a brain region critical for motivated behavior - and can be boosted with a nutritional intervention (N-acetylcysteine).

Hybridization probe capture is useful for discovery and surveillance of novel coronaviruses, and its unique strengths complement existing methods like amplicon sequencing and deep metagenomic sequencing.

Unhealthy lifestyle habits in adolescence associate with accelerated biological aging in young adulthood, but shared genetic factors underlying both lifestyle and biological aging may largely explain the observed associations.

The results reported here provide new and foundational insights into the neural architecture that underpins hippocampal dependent memory systems in the human brain by providing detailed maps that show how different cortical areas anatomically connect within the hippocampus.

Helminth infected hosts are an important cause of variation in the level, frequency and duration of Bordetella bronchiseptica shedding and dynamics of infection.

The voltage-gated sodium channel Na_v1.1 is identified as an essential component of the proprioceptive transmission machinery that is required in vivo for normal motor behavior.