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The two global regulators CRP and PhoP interact with each other to coordinate expression of essential virulence determinants of Mycobacterium tuberculosis.

In causal inference, the premotor cortex dynamically integrates prior information and current sensory inputs to infer hidden structures, and selectively updates sensory representations in the parietal cortex to support behavior.

Recordings from brainstem nuclei involved in chemosensory regulation of breathing in awake freely behaving mice show different complementary types of neuronal responses to hypercapnia in the retrotrapezoid nucleus and the rostral medullary raphe.

Individual human first-order tactile neurons, those that innervate the mechanoreceptors in the skin, can signal information about edge orientation differences at the limit of what people can feel and across a broad range of speeds relevant for real-world hand use.

A skewed B cell response in people living with HIV proceeds via an extrafollicular path and could result in reduced affinity B cell memory and antibody responses.

The core of histone acetyltransferase complex, NuA4, flexibly tethers various histone recognition modules, including the HAT module which is capable of binding nucleosomes marked by H3K4me3 and H3 acetylation.

Enriched dietary SFAs, specifically palmitic acid (PA), induce a broad and long-lived innate immune memory response which is harmful during disease exacerbated by inflammation, but beneficial for pathogen clearance.

A cryo-EM structure of the SARS-CoV-2 M protein, the most abundant protein in the viral envelope, provides insight into its essential role in virus assembly.

Dnajb6 is identified as a novel sick sinus syndrome causative gene that exhibits a unique expression pattern within a subpopulation of sinus node pacemaker cells.

Biological wastewater treatment plants are critical reservoirs of antimicrobial resistance (AMR), allowing for early detection and monitoring of resistant pathogens, whilst serving as models for understanding the segregation of mobile genetic elements through AMR.