Brad K Hulse, Hannah Haberkern ... Vivek Jayaraman
An analysis of the first complete synaptic resolution connectome of Drosophila's navigation circuit uncovers neural network motifs supporting broadly relevant sensorimotor computations.
Dawn M Wenzel, Douglas R Mackay ... Wesley I Sundquist
A comprehensive, quantitative, protein-protein interaction screen maps the network of interactions between human MIT domains and ESCRT-III C-terminal tails, and reveals MIT domain-containing protein cofactors for abscission and the 'No Cut' abscission checkpoint.
Philip J O'Herron, David A Hartmann ... Andy Y Shih
The diameter of individual or multiple arterioles can be rapidly controlled with high spatiotemporal resolution using optogenetics, providing a technique for the direct manipulation of blood flow independently of neural activity or pharmacological agents.
The muscle circadian clock regulates RNA-binding motif 20 (Rbm20) gene expression, providing a novel mechanism for titin splicing and isoform expression with implications for muscle structure and function.
A cryo-EM structure of the bacterial OmcZ cytochrome filament provides evidence for the possibility that cytochrome polymers had multiple origins in bacteria.
The most comprehensive neuroanatomical atlas on the expression of three glycoprotein hormone receptors, namely, TSHRs, LHCGRs, and FSHRs, was mapped using RNAscope, a technology that allows the detection of mRNA at single-transcript level.
In vivo imaging reveals that the synaptic vesicle cycle is a significant contributor to oxidative stress in sensory hair cells, rendering them susceptible to insults.
Outgroup conflict can negatively impact general reproductive behaviour, egg investment, and parental care, resulting in decreased reproductive output even in the absence of physical confrontations.
