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Two distinct genetic biocontrol methods work synergistically to yield a novel approach in the fight against pest organisms.

Self-reactive CD4⁺ thymocytes have a broad impact on the composition of medullary thymic epithelial cell (mTEC) subsets by acting upstream of Aire⁺ mTECs, which conditions the induction of T-cell tolerance.

A genetically sensitized drug screen identifies a circadian diabetes target and establishes a novel discovery pathway to treat β-cell failure.

The distributions of cellular neighborhood volumes in two very different multicellular species - snowflake yeast and Volvox carteri - are found to obey a common functional form arising from maximum entropy consideration, despite great differences in their cell division processes.

Glutamatergic neurons lacking the mitochondrial pyruvate carrier show reduced M-type potassium channel activity and hyperexcitability upon intense firing.

Individualized cross-frequency analyses reveal regionally specific slow oscillation–sleep spindle coupling precision as predictor for gross-motor learning dynamics.

Oxygen-independent (pseudohypoxic) HIF pathway activation is a core determinant of dysregulated collagen-structure function in human fibrosis.

Major neuronal subtypes in M1 show differential responses to reward and reward-associated stimuli and undergo cell-type-specific plasticity following associative learning.

The third causative gene ZNF862 was novelly identified for hereditary gingival fibromatosis in a large Chinese family.

The NDNF-like factor Nord is a Hedgehog-induced and extracellular-localized dosage-dependent BMP modulator that regulates Drosophila wing patterning and growth.