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The combination of molecular infrared fingerprinting and machine learning enables the detection of breast, bladder, prostate, and lung cancer based on liquid blood serum and plasma, providing a general framework for the minimally invasive investigation of oncological conditions.

Acetylcholine, released from cholinergic fibers originating from the medial septum, shapes social memory, and controls the CA2 hippocampal circuit via nicotinic receptors localized on GABAergic interneurons.

Central damage and sensory deprivation caused by noise-induced hearing loss in the pre-symptomatic Alzheimer's disease (AD) phase can compromise auditory cortex-hippocampal circuitry, targeting common pathogenetic pathways, thereby accelerating onset and progression of AD phenotype.

Combining cerebral organoid technology with cryo-correlative microscopy reveals the organization of cytoskeleton, membrane compartments, and protein synthesis machinery contributing to the rapid expansion of developing human axons.

Mutualistic viruses called virophages are common genome inhabitants of a marine protist, where they may protect host populations from giant viruses.

Echolocating toothed whales can detect and react to sudden prey movements during close approaches with speeds similar to ultra-fast tracking responses in human vision.

During Escherichia coli systemic infection, the replication of a minuscule fraction of the inoculum drives organ-specific clearance failures, systemic dissemination, and stochastic infection outcomes.

CA1 and PFC bridge the temporal gap between cue and reward delivery during trace conditioning according to different underlying coding principles and task-related activity is reactivated during awake Sharp-Wave Ripples.

Fluorescence fluctuation spectroscopy is implemented for detection of up to four molecular species, allowing users to quantify molecular interactions and stoichiometry of multicomponent complexes in live cells, in a wide range of biological processes, from membrane signaling to viral assembly.

COVID-19 mRNA vaccine-elicited T cells recognize variants of concern and phenotypically differ depending on number of vaccine doses and prior SARS-CoV-2 infection status.