Browse our latest research

Alternative splicing and the endoplasmic reticulum (ER)-associated protein degradation (ERAD) system represent essential, fat depot-specific components of the adipogenesis that are altered in preadipocytes from obese individuals with metabolic disease.

A specific SARS-CoV-2 proteins that affect the vascular permeability and impairs the functionality of other significant organs has been identified.

A proteomics-based approach identifies novel substrate proteins of the Lon protease in Caulobacter crescentus and reveals a critical role of Lon in regulating flagella assembly and stalk biogenesis during the cell cycle.

Assessments using chemogenetic and pharmacological approaches reveal that modulation of the activities of oxytocin neurons in the hypothalamus of the central nervous system could inhibit colorectal cancer progression in mice.

Across five experiments, Eurasian jays’ caching behaviour provides little evidence of the ability to integrate cues about a potential pilferer’s visual perspective and desire and, challenging previous findings, to respond to either of the two social cues independently.

Somatic stem and niche cells in the Drosophila ovary develop from common precursors through regulated proliferative expansion, followed by acquisition of position-specific behaviors, rather than through rigid early specification events.

A statistically principled approach developed to estimate phase of rhythmic signals in real-time shows robustness to multiple sources of error and also provides confidence criteria.

Single-molecule fluorescence experiments reveal transcription initiation proceeds via a 'bind-unwind-load-and-lock' mechanism where promoter DNA unwinds outside the RNA polymerase (RNAP) cleft, the unwound template-DNA loads into the cleft, and RNAP 'locks' the template-DNA by closing the RNAP clamp module.

Data exploring host and parasite signatures in the peripheral blood indicate that total parasite biomass is a better predictor of P. vivax-induced host responses and pathogenesis than peripheral parasitemia.

Retinal pigment epithelium flattening is an efficient solution adopted by the fast-developing zebrafish to enable folding of the eye primordia, which contrasts with the proliferation-based mechanism used by amniotes.