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    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Reprogramming: A perfect recipe for a corticospinal neuron

    Alfonso Aguilera, Marta Nieto
    A tailored cocktail of genes can reprogram a subset of progenitors to no longer produce glial cells and instead develop into neurons involved in motor control.
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    1. Neuroscience

    Motor Networks: When preparation pays off

    Mark M Churchland
    Computational principles shed light on why movement is preceded by preparatory activity within the neural networks that control muscles.
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    1. Biochemistry and Chemical Biology

    Immunotherapy: The power lies in the glycans

    Luca Unione, Jesús Jiménez-Barbero
    Glycans play an important role in modulating the interactions between natural killer cells and antibodies to fight pathogens and harmful cells.
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    1. Cell Biology

    Kidney Fibrosis: Lock out SIRT4

    Kaiqiang Zhao, Zhongjun Zhou
    The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.
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    1. Neuroscience

    Status Epilepticus: Stopping runaway seizures with a chill pill

    Gordon F Buchanan
    The neuropeptide neurotensin can reduce status epilepticus and its associated consequences through induction of therapeutic hypothermia when bound to a molecule that can penetrate the blood-brain barrier.
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    1. Neuroscience

    Sequential Movement: Reaching into the future

    Raeed H Chowdhury
    When carrying out a sequence of movements, humans can plan several steps in advance to make the movement smooth.
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    1. Plant Biology

    Seed Germination: Coping with salt stress

    Xiaoyan Liang, Caifu Jiang
    Salt stress delays seed germination in plants by increasing the hydrolysis of arginine-derived urea.
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    1. Neuroscience

    Locomotion: The rhythm is going to get you

    Mohini Sengupta
    Slow and fast movements are controlled by distinct sets of spinal V2a neurons with matching properties and connections.
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    1. Cell Biology

    Sensory Neurons: Addressing burning questions on axon regeneration

    Diána Kaszás, Balázs Enyedi
    Regeneration of sensory axons after a burn injury depends on early keratinocyte responses regulated by the wound microenvironment.
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    1. Cell Biology
    2. Developmental Biology

    Fertilization: Switching on lysosomes

    Deepak Adhikari, John Carroll
    The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition.
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