Evgeniya V Nazarova, Christine R Montague ... Brian C VanderVen
An unbiased forward genetic screen identified genes in Mycobacterium tuberculosis that are required for fatty acid import when the bacterium is residing within macrophages.
The protein Pat1 functions in the assembly of processing bodies, cellular membraneless organelles, by promoting the liquid–liquid phase separation of the DEAD-box ATPase Dhh1 and RNA.
Daan B Wesselink, Fiona MZ van den Heiligenberg ... Tamar R Makin
fMRI results show that despite arm amputation, and varying degrees of phantom sensations, canonical hand representation in primary somatosensory cortex is largely maintained.
Genomic deletions and gene conversions, caused by template switching associated with restarted DNA replication, are detected downstream of a collapsed replication fork and are suppressed by several conserved DNA helicases.
Jessica Ausborn, Natalia A Shevtsova ... Ilya A Rybak
A new computational model of brainstem control of locomotor speed and gait was developed to reproduce and explain recent experimental data and propose predictions for subsequent experimental testing.
Neurite geometry enables expansive and highly-branched neuronal structures to operate like single electrical compartments and simple linear integrators.
Nicole L Bertschi, Annemarie Voorberg-van der Wel ... Guglielmo Roma
Transcriptome profiling of malaria liver-stage parasites provides unprecedented knowledge on genes and pathways expressed in truly dormant hypnozoites and indicates that dormancy is associated with a switch in energy metabolism.
Mature myelin sheaths are scaffolded by the anillin-dependent assembly of septin filaments, thereby facilitating rapid nerve conduction in the healthy CNS.
The exogenous DNA DSBs improve meiotic chromosome pairing in mouse inter-subspecific hybrids, thus providing an evidence for a DSB-dependent mechanism of the PRDM9-controlled synapsis failure and infertility.
A genetic screen reveals that two predicted glycosyltransferases promote rosette development and prevent cell clumping in one of the closest living relatives of animals, the choanoflagellate S. rosetta.
