Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
The novel pre-training framework integrating sequential and geometric encoders significantly enhances protein engineering by accurately predicting variant effects and thermostability, outperforming existing zero-shot learning methods with minimal computational cost.
Sulfakinin-receptor1 signaling system alters the expression of odorant receptors in antenna to modulate the behavioral switch between foraging and mating in the oriental fruit fly.
Endothelial-specific supplementation with Aff3ir-ORF2 significantly ameliorated disturbed flow-induced endothelial activation and the development of atherosclerotic plaques, highlighting its promising therapeutic potential for the treatment of atherosclerosis.
William R Thomas, Troy Richter ... Liliana M Davalos
Adaptive gene expression in the common shrew hypothalamus connects energy homeostasis with reversible brain size changes in response to seasonal environmental challenges.
Target motion modulates monkey M1 neural dynamics during reaching, characterized by an orbital neural geometry composed of target-velocity-dependent tilting rings, suggesting that sensory information can be independently incorporated during motor generation.
When performance is matched, the attentional blink allows for greater integration of complex stimulus features than masking, reflecting spared recurrent processing during attentional versus perceptual impairments of conscious access.
Agnese Codutti, Mohammad A Charsooghi ... Stefan Klumpp
Microfluidics experiments and simulations show that magnetotactic bacteria are adapted to the geomagnetic field strength for optimal navigation in sediment environments.
