Rashmi Sukumaran, Achuthsankar S Nair, Moinak Banerjee
Genomic differences in stroke and its comorbid conditions can aid in refining the socio-economic interpretation of risk among different ethnicities and can assist in distinguishing their phenotypic variation.
ePAC, a novel cancer vaccine utilizing a mammalian-derived virus-like particle to co-deliver neoantigens and CpG-ODN, demonstrates strong antitumor efficacy in mouse models.
Thibaut Sellinger, Frank Johannes, Aurélien Tellier
The developed statistical method paves the way for next generation demographic and selection inference by combining information from several heritable genomic and epigenomic markers.
Cell biology and animal model analysis in mice shows that molecules involved in glycolytic metabolism could potentially serve as therapeutic targets for the treatment of neurological diseases.
Genetic analysis and knockout mouse model study identified calcyphosine-like (CAPSL) as a candidate disease gene in familial exudative vitreoretinopathy (FEVR), offering valuable insights into disease mechanisms.
Felix Michaud, Ruggiero Francavilla ... Lisa Topolnik
Early alterations in VIP interneuron activity may contribute to disruptions in CA1 hippocampal circuits and cognitive deficits in the 3xTg mouse model of Alzheimer's disease.
Harlan P Stevens, Carly V Winegar ... Stephen R Piccolo
Approximately 13% of figures in biology-related research articles are difficult for people with red/green colorblindness to decipher, but machine-learning models can help to identify these.