Browse our Research Articles

Page 128 of 1,381
    1. Evolutionary Biology

    The evolution of olfactory sensitivity, preferences, and behavioral responses in Mexican cavefish is influenced by fish personality

    Maryline Blin, Louis Valay ... Sylvie Rétaux
    Individual olfactory-driven behaviors, odor preferences, and olfactory sensitivity have rapidly evolved in blind Mexican cavefish, as a quantitative genetic trait.
    1. Neuroscience

    Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography

    Lukas Rier, Natalie Rhodes ... Matthew J Brookes
    The first neurodevelopmental study using a novel, wearable brain imaging system based on optically pumped magnetometers, shows age-related changes in neural oscillatory task responses and cortical functional connectivity.
    1. Evolutionary Biology

    Evolutionary druggability for low-dimensional fitness landscapes toward new metrics for antimicrobial applications

    Rafael F Guerrero, Tandin Dorji ... C Brandon Ogbunugafor
    Inspired by notions of 'druggability' from medicinal chemistry, two new metrics, drug applicability and variant vulnerability, utilize evolutionary perspectives and methods to improve attempts to treat infectious diseases.
    1. Neuroscience

    Ingestible pills reveal gastric correlates of emotions

    Giuseppina Porciello, Alessandro Monti ... Salvatore Maria Aglioti
    Direct measures of inner gastrointestinal signals via ingestible capsules highlight the role of stomach pH in shaping human feelings of disgust, fear and happiness.
    1. Chromosomes and Gene Expression

    The role of RNA in the maintenance of chromatin domains as revealed by antibody-mediated proximity labelling coupled to mass spectrometry

    Rupam Choudhury, Anuroop Venkateswaran Venkatasubramani ... Axel Imhof
    Proximity biotinylation of the Drosophila centromere suggests a role of RNA helicases, centromeric transcripts, and centromeric R-loops for centromere function.
    1. Cancer Biology
    2. Genetics and Genomics

    DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers

    Jose Mario Bello Pineda, Robert K Bradley
    DUX4 expression is a common feature of metastatic tumors, where it is significantly associated with immune cell exclusion, decreased objective response to immune checkpoint blockade, and reduced patient survival.
    1. Neuroscience

    The archerfish uses motor adaptation in shooting to correct for changing physical conditions

    Svetlana Volotsky, Opher Donchin, Ronen Segev
    The archerfish adapts with egocentric reference frame to correct for different conditions during shot above water level.
    1. Stem Cells and Regenerative Medicine

    Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells

    Fanny-Mei Cloarec-Ung, Jamie Beaulieu ... David JHF Knapp
    Precision genome editing in human hematopoietic stem and progenitor cells can achieve near-perfect efficiency with tunable zygosity, thus enabling isogenic disease modeling for monogenic blood disorders and improving therapeutic applications.
    1. Epidemiology and Global Health

    The impact of surgery and oncological treatment on risk of type 2 diabetes onset in patients with colorectal cancer: nationwide cohort study in Denmark

    Caroline Krag, Maria Saur Svane ... Tinne Laurberg
    Treatment of colorectal cancer with colonic resection compared with rectal resection results in sligthly increased T2D risk, whereas chemotherapy treatment does not impact risk of developing T2D.
    1. Developmental Biology

    Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation

    Xianwei Chen, Yanfeng Li ... Zhenguo Wu
    Styxl2, a sarcomeric muscle-specific pseudophosphatase in vertebrates, functions in sarcomere assembly by promoting protein degradation of non-muscle myosin IIs.