Browse our Research Articles

Page 127 of 1,403
    1. Cell Biology
    2. Developmental Biology

    Caenorhabditis elegans SEL-5/AAK1 regulates cell migration and cell outgrowth independently of its kinase activity

    Filip Knop, Apolena Zounarová ... Marie Macůrková
    The SEL-5/AAK1 kinase unexpectedly influences Wnt signalling-dependent processes in a multicellular organism without using its enzymatic activity.
    1. Neuroscience

    The components of an electrical synapse as revealed by expansion microscopy of a single synaptic contact

    Sandra P Cárdenas-García, Sundas Ijaz, Alberto E Pereda
    Anatomical study reveals a new perspective on the definition of an electrical synapse where, in addition to the communicating role of gap junctions, additional cellular structures might be involved in the support and regulation of these intercellular channels.
    1. Chromosomes and Gene Expression

    Artificially inserted strong promoter containing multiple G-quadruplexes induces long-range chromatin modification

    Shuvra Shekhar Roy, Sulochana Bagri ... Shantanu Chowdhury
    Non-duplex DNA structures induce distant chromatin-chromatin interactions and gene activation over long distances.
    1. Developmental Biology
    2. Neuroscience

    Multiple guidance mechanisms control axon growth to generate precise T-shaped bifurcation during dorsal funiculus development in the spinal cord

    Bridget M Curran, Kelsey R Nickerson ... Le Ma
    Formation of dorsal axonal tracts in the spinal cord depends on multiple guidance mechanisms that control growth direction of bifurcating axons in the dorsal root entry zone.
    1. Immunology and Inflammation

    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

    Chan-Su Park, Jian Guan ... Scheherazade Sadegh-Nasseri
    Fam49b is a critical regulator of selection process to ensure normal thymocyte development and peripheral T cells survival.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Hyperglycemia induced cathepsin L maturation linked to diabetic comorbidities and COVID-19 mortality

    Qiong He, Miao-Miao Zhao ... Jin-Kui Yang
    High glucose levels promote CTSL maturation and translocation from the endoplasmic reticulum to the lysosome via the ER-Golgi-lysosome axis.
    1. Evolutionary Biology

    Biocalcification in porcelaneous foraminifera

    Zofia Dubicka, Jarosław Tyszka ... Ulf Bickmeyer
    Porcelaneous foraminifera, marine calcifiers, reveal their biomineralization secrets.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    OpenNucleome for high-resolution nuclear structural and dynamical modeling

    Zhuohan Lao, Kartik D Kamat ... Bin Zhang
    An open-source tool for computational simulations of the human genome has been introduced, enabling the characterization of complex nuclear environments and the interpretation of experimental observations.
    1. Cancer Biology

    RGS10 deficiency facilitates distant metastasis by inducing epithelial–mesenchymal transition in breast cancer

    Yang Liu, Yi Jiang ... Xi Gu
    The novel action of RGS10 in epithelial–mesenchymal transition in breast cancer is dependent on LNC2 and miR-539-5p, which is identified as a prognostic biomarker for early distant metastasis in breast cancer.
    1. Cell Biology
    2. Neuroscience

    Plasticity-induced actin polymerization in the dendritic shaft regulates intracellular AMPA receptor trafficking

    Victor C Wong, Patrick R Houlihan ... Erin K O'Shea
    Glutamate receptor-containing vesicles are positioned in the dendritic shaft near sites of synaptic activity by F-actin.