Browse our Research Articles

Page 13 of 1,400
    1. Developmental Biology

    Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila

    Pengzhen Dong, Yue Li ... Hai Huang
    Long-range communication between neighboring organs orchestrates the disciplined migration of stem cells.
    1. Developmental Biology

    Oviductin sets the species-specificity of the mammalian zona pellucida

    Daniel de la Fuente, Maria Maroto ... Alfonso Gutierrez-Adan
    The oocyte zona pellucida needs to interact with an oviduct protein called OVGP1 to ensure that only sperm from the same species can fertilize the egg.
    1. Microbiology and Infectious Disease

    A within-host infection model to explore tolerance and resistance

    David Duneau, Pierre DM Lafont ... Jean-Baptiste Ferdy
    A mathematical model of pathogen within-host dynamics and experimental validations elucidates the interplay between immune response, damage and pathogen proliferation, highlighting the limitations of current experimental proxies and proposing new methods to better understand host resistance and disease tolerance.
    1. Cell Biology

    Clearance of protein aggregates during cell division

    Shoukang Du, Yuhan Wang ... Ting Gang Chew
    ER aggregates confined in the nucleus are cleared via ER reorganization when cells progress through mitosis and cytokinesis.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A general mechanism for initiating the bacterial general stress response

    Rishika Baral, Kristin Ho ... Niels Bradshaw
    A coiled-coil-based transduction mechanism is identified for a serine/threonine phosphatase that controls a bacterial stress response, suggesting that phosphatases are part of a modularly exchangeable toolkit for bacterial signaling.
    1. Neuroscience

    Different roles of D1/D2 medium spiny neurons in the nucleus accumbens in pair bond formation of male mandarin voles

    Lizi Zhang, Yishan Qu ... Fa-Dao Tai
    In male mandarin voles, D1 and D2 medium spiny neurons within the nucleus accumbens shell exert distinct influences on pair bond formation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Upstream open reading frames buffer translational variability during Drosophila evolution and development

    Yuanqiang Sun, Yuange Duan ... Jian Lu
    Upstream open reading frames (uORFs) function as regulatory elements that buffer translation variability, stabilizing protein expression across animal developmental stages and evolutionary timescales.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Deep sequencing of yeast and mouse tRNAs and tRNA fragments using OTTR

    Hans Tobias Gustafsson, Lucas Ferguson ... Oliver J Rando
    A recently developed RNA cloning protocol efficiently captures both intact and fragmented tRNAs.
    1. Neuroscience

    Hierarchy between forelimb premotor and primary motor cortices and its manifestation in their firing patterns

    Akiko Saiki-Ishikawa, Mark Agrios ... Andrew Miri
    During reaching in mice, forelimb premotor cortex has a stronger influence on primary motor cortex than vice versa, but several functional connectivity measures fail to reflect this asymmetry.
    1. Microbiology and Infectious Disease

    Chalkophore-mediated respiratory oxidase flexibility controls M. tuberculosis virulence

    John A Buglino, Yaprak Ozakman ... Michael S Glickman
    M. tuberculosis produces a copper binding diisonitrile chalkophore to maintain the copper-dependent respiratory oxidase during infection, identifying a pathogen strategy that defends oxidative phosphorylation against host attack.