Catherine Sirois-Delisle, Susan CC Gordon, Jeremy Kerr
Across continents, half of odonate species shifted both ranges and phenologies in response to climate warming, with southern species and those experiencing less temperature variability shifting ranges more strongly.
An integrative analysis of scRNA-seq and spatial transcriptomics provides complementary views into the biology of pre-clinical colorectal cancer models in mice with possible applications to the human system.
Tanja Nielsen, Anaïs Kervadec ... Alexandre R Colas
Cross-species functional genomics identify ribosomal protein genes as key regulators of cardiomyocyte proliferation and heart development, implicating them as candidate modifiers for HLHS and revealing new avenues for therapeutic discovery.
Austin Tedman, John A Olson III ... Jonathan P Schlebach
Combining deep mutational scanning with CRISPR, interactome measurements, and electrophysiology reveals nuanced effects of the lectin chaperone calnexin on the pharmacological properties of 232 cystic fibrosis variants.
Roland Zimm, Vitória Tobias Santos, Nicolas Goudemand
Shark dentition is a complex and hyper-diverse trait integrating multiple spatial levels, with mid-scale features being most crucial for functional adaptation, revealing evolutionary patterns that offer insights into distinct ecological strategies.
Metagenomic sequencing of stool samples from 225 hospital patients and healthy volunteers reveals the impact of different antimicrobial exposures on the gut microbiome.