Daniel de la Fuente, Maria Maroto ... Alfonso Gutierrez-Adan
The oocyte zona pellucida needs to interact with an oviduct protein called OVGP1 to ensure that only sperm from the same species can fertilize the egg.
David Duneau, Pierre DM Lafont ... Jean-Baptiste Ferdy
A mathematical model of pathogen within-host dynamics and experimental validations elucidates the interplay between immune response, damage and pathogen proliferation, highlighting the limitations of current experimental proxies and proposing new methods to better understand host resistance and disease tolerance.
A coiled-coil-based transduction mechanism is identified for a serine/threonine phosphatase that controls a bacterial stress response, suggesting that phosphatases are part of a modularly exchangeable toolkit for bacterial signaling.
Upstream open reading frames (uORFs) function as regulatory elements that buffer translation variability, stabilizing protein expression across animal developmental stages and evolutionary timescales.
During reaching in mice, forelimb premotor cortex has a stronger influence on primary motor cortex than vice versa, but several functional connectivity measures fail to reflect this asymmetry.
John A Buglino, Yaprak Ozakman ... Michael S Glickman
M. tuberculosis produces a copper binding diisonitrile chalkophore to maintain the copper-dependent respiratory oxidase during infection, identifying a pathogen strategy that defends oxidative phosphorylation against host attack.