Browse our Research Articles

Page 13 of 1,441
    1. Evolutionary Biology

    The holocephalan ratfish endoskeleton shares trabecular and areolar mineralization patterns, but not tesserae, with elasmobranchs little skate and catshark

    Oghenevwogaga Joseph Atake, Fidji Berio ... B Frank Eames
    Novel and published data confirm that cartilaginous fishes (chondrichthyans) from many different clades share interesting skeletal features that are similar to bone, but some 'classic' chondrichthyan features are not shared.
    1. Neuroscience

    Single-cell transcriptome sequencing for opening the blood-brain barrier through specific mode electroacupuncture stimulation

    Congcong Ma, Zhaoxing Jia ... Xianming Lin
    Single-cell transcriptome sequencing results of rats intervened with specific mode electroacupuncture (an emerging method for opening the blood-brain barrier).
    1. Physics of Living Systems

    Toward stable replication of genomic information in pools of RNA molecules

    Ludwig Burger, Ulrich Gerland
    Theoretical and computational analyses reveal environmental, compositional, kinetic, and thermodynamic constraints on a scenario where sequence information collectively stored in pools of RNA molecules is replicated via non-enzymatic RNA ligation.
    1. Developmental Biology
    2. Evolutionary Biology

    Molecular dynamics of the matrisome across sea anemone life history

    Bruno Gideon Bergheim, Alison G Cole ... Suat Özbek
    Integrated proteomic and single-cell transcriptomic analyses define the Nematostella vectensis matrisome and reveal conserved extracellular matrix functions driving life cycle transitions in this non-bilaterian model.
    1. Neuroscience

    Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms

    Martin Breyton, Jan Fousek ... Viktor Jirsa
    Brain fluidity metrics provide an accessible and reliable marker of consciousness, offering a practical alternative to perturbational complexity for clinical and research applications.
    1. Stem Cells and Regenerative Medicine

    Chromatin activity of IκBα mediates the exit from naïve pluripotency

    Luis G Palma, Daniel Alvarez-Villanueva ... Anna Bigas
    The development of novel separation-of-function mutants has uncovered non-canonical chromatin roles of IκBα in regulating mouse embryonic stem cell pluripotency and differentiation, independently of the classical NF-κB pathway.
    1. Stem Cells and Regenerative Medicine

    Stabilisation of HIF signalling in the mouse epicardium extends embryonic potential and neonatal heart regeneration

    Elisabetta Gamen, Eleanor L Price ... Paul R Riley
    Extending hypoxia signalling after birth extends the window of heart regeneration.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders

    Matthew B McDougal, Ian N Boys ... John W Schoggins
    Evolutionary changes in RNA binding and antiviral activity result in diverse IFIT1 functions across mammals, even among closely related species.
    1. Neuroscience

    Blood pressure variability compromises vascular function in middle-aged mice

    Perenkita J Mendiola, Philip O'Herron ... Jessica A Filosa
    Chronic variations in blood pressure compromise brain health.
    1. Neuroscience

    Sequential temporal anticipation characterized by neural power modulation and in recurrent neural networks

    Xiangbin Teng, Ru-Yuan Zhang
    Predicting key future moments requires ignoring most irrelevant time, and alpha and beta power modulations encode sequential temporal landmarks via a gain-control mechanism that suppresses these irrelevant periods.