Browse our Research Articles

Page 130 of 1,381
    1. Neuroscience

    Genetically defined nucleus incertus neurons differ in connectivity and function

    Emma D Spikol, Ji Cheng ... Marnie E Halpern
    Transgenic zebrafish generated by targeted genomic integration distinguish neuronal subtypes in the nucleus incertus that differ in their connections and functional properties.
    1. Developmental Biology
    2. Genetics and Genomics

    Fetal growth delay caused by loss of non-canonical imprinting is resolved late in pregnancy and culminates in offspring overgrowth

    Ruby Oberin, Sigrid Petautschnig ... Patrick S Western
    Growth-delayed offspring generated from eggs that lacked normal epigenetic programming exhibited a remarkable capacity to undergo late gestational fetal growth recovery, despite inefficient placental function.
    1. Computational and Systems Biology
    2. Neuroscience

    Theoretical principles explain the structure of the insect head direction circuit

    Pau Vilimelis Aceituno, Dominic Dall'Osto, Ioannis Pisokas
    Three theoretical principles explain the neural activity observed in the head direction circuit of insects, the connectivity pattern underlying the circuit, and how the ubiquitous eight-column circuit structure emerged from evolutionary processes.
    1. Neuroscience

    Neurexins control the strength and precise timing of glycinergic inhibition in the auditory brainstem

    He-Hai Jiang, Ruoxuan Xu ... Fujun Luo
    Neurexins are essential for shaping the functional properties of glycinergic synapse in the auditory brainstem, further attesting their universal role as critical presynaptic organizers in all major fast chemical synapses.
    1. Plant Biology

    H1 restricts euchromatin-associated methylation pathways from heterochromatic encroachment

    C Jake Harris, Zhenhui Zhong ... Steven E Jacobsen
    The efficient deployment of RdDM for transposon silencing is hierarchically controlled by the linker histone H1.
    1. Ecology

    The larva and adult of Helicoverpa armigera use differential gustatory receptors to sense sucrose

    Shuai-Shuai Zhang, Pei-Chao Wang ... Chen-Zhu Wang
    The sweet taste receptors in the cotton bollworm (Helicoverpa armigera) are evolved to adapt towards the larval and adult foods with different types and amounts of sugar.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease

    Kejia Zhang, Patrick Eldin ... Dragony Fu
    SARS-CoV-2 infection reduces the intracellular levels of a human tRNA modification enzyme and alters host tRNA modification profiles.
    1. Neuroscience

    Reactivation strength during cued recall is modulated by graph distance within cognitive maps

    Simon Kern, Juliane Nagel ... Gordon B Feld
    Items retrieved from cognitive maps are reactivated simultaneously or sequentially depending on the performance, where in the first case the reactivation strength reflects the distance within the map.
    1. Cancer Biology
    2. Cell Biology

    mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming

    Helmut Bischof, Selina Maier ... Robert Lukowski
    A novel role of the mitochondrial BKCa channel involves the metabolic reprogramming of breast cancer cells, facilitating their unrestricted proliferation and O2-independence, which is also of potential clinical relevance.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Tuning apicobasal polarity and junctional recycling in the hemogenic endothelium orchestrates the morphodynamic complexity of emerging pre-hematopoietic stem cells

    Léa Torcq, Sara Majello ... Anne A Schmidt
    Pre-hematopoietic stem cells emerge from the aortic floor according to two radically different morphodynamics whose biomechanics rely on controlling apicobasal polarity in hemogenic precursors, which may impact on their fate.