Browse our Research Articles

Mesolimbic dopamine ramps emerge only when overall event rates are high, thereby providing a key constraint on theories of dopamine signaling.

A newly discovered long noncoding RNA lnc-FANCI-2 suppresses RAS signaling to modulate Akt and Erk1/2 phosphorylation in high-risk HPV cervical cancer, consequently regulating HPV carcinogenesis.

Early immune pressure and co-occurring mutations drive changes in hepatitis C virus fitness and evolution, revealing key dynamics in the establishment of chronic infection.

Convolutional embedding models efficiently capture wide sequence context in antibody somatic hypermutation, avoiding exponential k-mer parameter scaling and eliminating the need for per-site modeling.

Gut dysbiosis and specific microbiota composition promoted the absorption of excess palmitic acid in the ileum, driving its accumulation in the serum.

Engineering self-amplifying RNA to intrinsically disarm the innate immune pathways it triggers enables durable, externally controlled gene expression with reduced cytotoxicity and cytokine release, eliminating the need for exogenous immunosuppressants.

Orexin neurons precisely track body movement across behavioral and metabolic states, revealing a neural mechanism that links motor activity to arousal and energy resources.

Reversible synaptic plasticity between sensory neurons and interneurons, switching between inhibitory and excitatory, underpins the neural basis of salt concentration memory-dependent preference reversal in Caenorhabditis elegans.

Enalapril combats the effects of senescence by activating the pSmad1/5/9–antioxidative gene axis, enhancing antioxidative defenses and promoting cell proliferation, thereby supporting healthy aging.

Molecular profiling with omics approaches reveals the resemblance between neuroendocrine malignancies and solitary fibrous tumors, rare soft tissue cancers with no effective treatment options.