Browse our Research Articles

Page 207 of 1,402
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Identification of key yeast species and microbe–microbe interactions impacting larval growth of Drosophila in the wild

    Ayumi Mure, Yuki Sugiura ... Yukako Hattori
    The growth of wild Drosophila larvae on fruits is promoted by a yeast releasing essential nutrients extracellularly or by a stable association with a nutrient-providing bacterium established by microbe–microbe interactions.
    1. Neuroscience

    FSHβ links photoperiodic signaling to seasonal reproduction in Japanese quail

    Gaurav Majumdar, Timothy A Liddle ... Tyler Stevenson
    Molecular analyses reveal the neuroendocrine control of seasonal life-history transitions in birds.
    1. Genetics and Genomics
    2. Neuroscience

    Sensory neurons couple arousal and foraging decisions in Caenorhabditis elegans

    Elias Scheer, Cornelia I Bargmann
    A long-term arousal state is linked to the acute decision to leave a food patch by sensory neurons that integrate neuromodulatory information, food intake, and environmental signals.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Soil-borne fungi alter the apoplastic purinergic signaling in plants by deregulating the homeostasis of extracellular ATP and its metabolite adenosine

    Christopher Kesten, Valentin Leitner ... Clara Sanchez-Rodriguez
    Biochemical and in vivo physiology imaging reveal that plant pathogens actively imbalance the apoplastic eAdo/eATP levels as a virulence mechanism.
    1. Neuroscience

    Imaging microglia surveillance during sleep-wake cycles in freely behaving mice

    Xiaochun Gu, Zhong Zhao ... Heping Cheng
    Using long-term in vivo imaging with miniature two-photon microscopy, microglia surveillance is sleep state-dependent and stress-induced in freely behaving mice, regulated by the locus coeruleus-norepinephrine system and β2-adrenergic receptors signaling.
    1. Structural Biology and Molecular Biophysics

    How accurately can one predict drug binding modes using AlphaFold models?

    Masha Karelina, Joseph J Noh, Ron O Dror
    AlphaFold 2 models capture binding pocket structures accurately but fare poorly when used to predict ligand-binding poses.
    1. Neuroscience

    Microglia facilitate and stabilize the response to general anesthesia via modulating the neuronal network in a brain region-specific manner

    Yang He, Taohui Liu ... Bo Peng
    Microglia differentially modulate the neuronal activities via P2Y12 and its downstream Ca2+ signaling in a brain region-specific manner, which facilitates and stabilizes the response to general anesthesia.
    1. Neuroscience

    PAK3 downregulation induces cognitive impairment following cranial irradiation

    Haksoo Lee, Hyunkoo Kang ... BuHyun Youn
    p21-activated kinase 3 (PAK3) is a factor related to radiation-induced cognitive decline, and it has been found that regulating it leads to the recovery of cognitive decline induced by radiation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates

    Wenjie Xu, Chenglong Zhu ... Kun Wang
    The hadal snailfish rapidly evolved and adapted to extreme deep-sea environments, modifying crucial genes and enhancing tolerance to high-hydrostatic pressure through ferritin gene duplication.
    1. Medicine

    Effects of neoadjuvant stereotactic body radiotherapy plus adebrelimab and chemotherapy for triple-negative breast cancer: A pilot study

    Guanglei Chen, Xi Gu ... Caigang Liu
    Stereotactic body radiotherapy combined with immunotherapy and chemotherapy in neoadjuvant setting exhibited a promising anti-tumor activity and an acceptable safety profile in triple-negative breast cancer patients.