Gene expression in nematodes during cold-induced dormancy is proposed to be regulated at the transcription level, partly involving the activation of unfolded protein response (UPR) through the IRE-1/XBP-1 signaling pathway.
Simon Rethemeier, Sonja Fritzsche ... Vera S Hunnekuhl
Genetic labeling and molecular analyses characterize the dynamics of embryonic central complex-forming type II neuroblast lineages in Tribolium castaneum.
Sakshi Shambhavi, Sudipta Mondal ... Rajan Sankaranarayanan
Dip2 regulates PKC signalling through specific DAG acyl chain compositions—a crucial pathway, which emerged approximately 1.2 billion years ago, marking the advent of selective DAG-based signalling in eukaryotes.
Distinct seasonal peaks and sex-specific interactions reveal that cohesive female groups drive rapid local spread while male connectors facilitate intergroup transmission, underscoring the need for tailored disease control strategies.
The novel pre-training framework integrating sequential and geometric encoders significantly enhances protein engineering by accurately predicting variant effects and thermostability, outperforming existing zero-shot learning methods with minimal computational cost.
Sulfakinin-receptor1 signaling system alters the expression of odorant receptors in antenna to modulate the behavioral switch between foraging and mating in the oriental fruit fly.