Browse our Research Articles

Page 25 of 1,400
    1. Immunology and Inflammation

    RAG suppresses group 2 innate lymphoid cells

    Aaron M Ver Heul, Madison Mack ... Brian S Kim
    Developmental imprinting controls innate type 2 immune function and allergic inflammation.
    1. Cell Biology

    Reprograming gene expression in ‘hibernating’ C. elegans involves the IRE-1/XBP-1 pathway

    Melanie Lianne Engelfriet, Yanwu Guo ... Rafal Ciosk
    Gene expression in nematodes during cold-induced dormancy is proposed to be regulated at the transcription level, partly involving the activation of unfolded protein response (UPR) through the IRE-1/XBP-1 signaling pathway.
    1. Developmental Biology
    2. Evolutionary Biology

    Differences in size and number of embryonic type II neuroblast lineages correlate with divergent timing of central complex development between beetle and fly

    Simon Rethemeier, Sonja Fritzsche ... Vera S Hunnekuhl
    Genetic labeling and molecular analyses characterize the dynamics of embryonic central complex-forming type II neuroblast lineages in Tribolium castaneum.
    1. Cell Biology

    Emergence of Dip2-mediated specific DAG-based PKC signalling axis in eukaryotes

    Sakshi Shambhavi, Sudipta Mondal ... Rajan Sankaranarayanan
    Dip2 regulates PKC signalling through specific DAG acyl chain compositions—a crucial pathway, which emerged approximately 1.2 billion years ago, marking the advent of selective DAG-based signalling in eukaryotes.
    1. Cell Biology
    2. Developmental Biology

    Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

    Qian Wang, Hongge Li ... Xin Zhang
    FGF signaling drives lens development by recruiting Grb2 through Shc1, Frs2, and Shp2 to regulate transcription and cytoskeletal arrangements.
    1. Ecology

    Quantifying feral pig interactions to inform disease transmission networks

    Tatiana Proboste, Abigail Turnlund ... Ricardo J Soares-Magalhaes
    Distinct seasonal peaks and sex-specific interactions reveal that cohesive female groups drive rapid local spread while male connectors facilitate intergroup transmission, underscoring the need for tailored disease control strategies.
    1. Plant Biology

    Interdependence of plasma membrane nanoscale dynamics of a kinase and its cognate substrate underlies Arabidopsis response to viral infection

    Marie-Dominique Jolivet, Anne Flore Deroubaix ... Véronique Germain
    Dynamic lateral diffusion of the kinase and its substrate in the plasma membrane are crucial for a proper signaling response.
    1. Computational and Systems Biology

    Semantical and geometrical protein encoding toward enhanced bioactivity and thermostability

    Yang Tan, Bingxin Zhou ... Liang Hong
    The novel pre-training framework integrating sequential and geometric encoders significantly enhances protein engineering by accurately predicting variant effects and thermostability, outperforming existing zero-shot learning methods with minimal computational cost.
    1. Ecology

    The neuropeptide sulfakinin is a peripheral regulator of insect behavioral switch between mating and foraging

    Hong-Fei Li, Bao Dong ... Hong-Bo Jiang
    Sulfakinin-receptor1 signaling system alters the expression of odorant receptors in antenna to modulate the behavioral switch between foraging and mating in the oriental fruit fly.
    1. Neuroscience

    Temporal dynamics analysis reveals that concurrent working memory load eliminates the Stroop effect through disrupting stimulus-response mapping

    Yafen Li, Yixuan Lin ... Antao Chen
    The concurrent working memory load influences the Stroop conflict processing during the later stage of stimulus-response mapping.