Browse our Research Articles

Drastic differences in genetic and epigenetic fitness of MYC-driven cancer cells in 3D vs 2D culture.

Developmental imprinting controls innate type 2 immune function and allergic inflammation.

Gene expression in nematodes during cold-induced dormancy is proposed to be regulated at the transcription level, partly involving the activation of unfolded protein response (UPR) through the IRE-1/XBP-1 signaling pathway.

Genetic labeling and molecular analyses characterize the dynamics of embryonic central complex-forming type II neuroblast lineages in Tribolium castaneum.

Dip2 regulates PKC signalling through specific DAG acyl chain compositions—a crucial pathway, which emerged approximately 1.2 billion years ago, marking the advent of selective DAG-based signalling in eukaryotes.

FGF signaling drives lens development by recruiting Grb2 through Shc1, Frs2, and Shp2 to regulate transcription and cytoskeletal arrangements.

Distinct seasonal peaks and sex-specific interactions reveal that cohesive female groups drive rapid local spread while male connectors facilitate intergroup transmission, underscoring the need for tailored disease control strategies.

Dynamic lateral diffusion of the kinase and its substrate in the plasma membrane are crucial for a proper signaling response.

The novel pre-training framework integrating sequential and geometric encoders significantly enhances protein engineering by accurately predicting variant effects and thermostability, outperforming existing zero-shot learning methods with minimal computational cost.

Sulfakinin-receptor1 signaling system alters the expression of odorant receptors in antenna to modulate the behavioral switch between foraging and mating in the oriental fruit fly.